Phase-corrected buffer averaging for enhanced OCT angiography using FDML laser

Yusi Miao; Mahsa Siadati; Jun Song; Da Ma; Yifan Jian; Mirza Faisal Beg; Marinko V. Sarunic; Myeong Jin Ju

doi:10.1364/OL.430915

Phase-corrected buffer averaging for enhanced OCT angiography using FDML laser

Yusi Miao, Mahsa Siadati, Jun Song, Da Ma, Yifan Jian, Mirza Faisal Beg, Marinko V. Sarunic, Myeong Jin Ju

Ophthalmology

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Megahertz-rate optical coherence tomography angiography (OCTA) is highly anticipated as an ultrafast imaging tool in clinical settings. However, shot-noise-limited sensitivity is inevitably reduced in high-speed imaging systems. In this Letter, we present a coherent buffer averaging technique for use with a Fourier-domain mode-locked (FDML) laser to improve OCTA contrast at 1060 nm MHz-rate retinal imaging. Full characterization of spectral variations among the FDML buffers and a numerical correction method are also presented, with the results demonstrating a 10-fold increase in the phase alignment among buffers. Coherent buffer averaging provided better OCTA contrast than the conventional multi-frame averaging approach with a faster acquisition time.

Original language	English (US)
Pages (from-to)	3833-3836
Number of pages	4
Journal	Optics Letters
Volume	46
Issue number	16
DOIs	https://doi.org/10.1364/OL.430915
State	Published - Aug 15 2021

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics

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10.1364/OL.430915

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abstract = "Megahertz-rate optical coherence tomography angiography (OCTA) is highly anticipated as an ultrafast imaging tool in clinical settings. However, shot-noise-limited sensitivity is inevitably reduced in high-speed imaging systems. In this Letter, we present a coherent buffer averaging technique for use with a Fourier-domain mode-locked (FDML) laser to improve OCTA contrast at 1060 nm MHz-rate retinal imaging. Full characterization of spectral variations among the FDML buffers and a numerical correction method are also presented, with the results demonstrating a 10-fold increase in the phase alignment among buffers. Coherent buffer averaging provided better OCTA contrast than the conventional multi-frame averaging approach with a faster acquisition time.",

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AU - Miao, Yusi

AU - Siadati, Mahsa

AU - Song, Jun

AU - Ma, Da

AU - Jian, Yifan

AU - Beg, Mirza Faisal

AU - Sarunic, Marinko V.

AU - Jin Ju, Myeong

PY - 2021/8/15

Y1 - 2021/8/15

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AB - Megahertz-rate optical coherence tomography angiography (OCTA) is highly anticipated as an ultrafast imaging tool in clinical settings. However, shot-noise-limited sensitivity is inevitably reduced in high-speed imaging systems. In this Letter, we present a coherent buffer averaging technique for use with a Fourier-domain mode-locked (FDML) laser to improve OCTA contrast at 1060 nm MHz-rate retinal imaging. Full characterization of spectral variations among the FDML buffers and a numerical correction method are also presented, with the results demonstrating a 10-fold increase in the phase alignment among buffers. Coherent buffer averaging provided better OCTA contrast than the conventional multi-frame averaging approach with a faster acquisition time.

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Phase-corrected buffer averaging for enhanced OCT angiography using FDML laser

Abstract

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