Phase-corrected buffer averaging for enhanced OCT angiography using FDML laser

Yusi Miao, Mahsa Siadati, Jun Song, Da Ma, Yifan Jian, Mirza Faisal Beg, Marinko V. Sarunic, Myeong Jin Ju

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Megahertz-rate optical coherence tomography angiography (OCTA) is highly anticipated as an ultrafast imaging tool in clinical settings. However, shot-noise-limited sensitivity is inevitably reduced in high-speed imaging systems. In this Letter, we present a coherent buffer averaging technique for use with a Fourier-domain mode-locked (FDML) laser to improve OCTA contrast at 1060 nm MHz-rate retinal imaging. Full characterization of spectral variations among the FDML buffers and a numerical correction method are also presented, with the results demonstrating a 10-fold increase in the phase alignment among buffers. Coherent buffer averaging provided better OCTA contrast than the conventional multi-frame averaging approach with a faster acquisition time.

Original languageEnglish (US)
Pages (from-to)3833-3836
Number of pages4
JournalOptics Letters
Issue number16
StatePublished - Aug 15 2021

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics


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