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Phenotype switch in acute lymphoblastic leukaemia associated with 3 years of persistent CAR T cell directed-CD19 selective pressure

Research output: Contribution to journalLetterpeer-review

Original languageEnglish (US)
Pages (from-to)333-336
Number of pages4
JournalBritish Journal of Haematology
Volume186
Issue number2
DOIs
StatePublished - Jul 2019

Funding

We wish to thank the OHSU Histopathology Core services for the processing of the tissue. OML and KP analysed the data and wrote the manuscript, TF obtained the tissue samples and contributed to the writing of the manuscript, JD analysed the immunophenotype and contributed to the writing of the manuscript, RP contributed essential next-generation sequencing, analysed the data and contributed to the writing of the manuscript, RAG and BHC designed the study, analysed the data and contributed to the writing of the manuscript. OML, PK, TF, JD, RP, RAG and BHC have no competing financial interests.

Funders
Center for Outcomes Research and Evaluation, Yale School of Medicine
Oregon State University/Oregon Health and Science University
Bayer Healthcare

    Keywords

    • CAR T cells
    • KMT2A
    • PHF6
    • PTPN11
    • lineage switch

    ASJC Scopus subject areas

    • Hematology

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