Plasmapheresis to treat hypertriglyceridemia in a child with diabetic ketoacidosis and pancreatitis

Riad Lutfi, Jennifer Huang, Hector R. Wong

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


A 10-year-old girl presented with diabetic ketoacidosis, shock, and severe abdominal pain. She was found to have acute pancreatitis and acute kidney injury after shock resuscitation and severe persistent hypertriglyceridemia. The severe hypertriglyceridemia was treated with 1 course of plasmapheresis, which corrected the triglyceride level and was temporally associated with improvement of the abdominal pain and renal dysfunction. Diabetes is known to contribute to an elevated triglyceride level, especially in the setting of an underlying lipid disorder. However, no such disorders were found in this patient. To the best of our knowledge, this is the first report of a pediatric patient presenting with the triad of severe hypertriglyceridemia, diabetic ketoacidosis, and pancreatitis treated successfully with plasmapheresis.

Original languageEnglish (US)
Pages (from-to)e195-e198
Issue number1
StatePublished - Jan 2012
Externally publishedYes


  • Acute pancreatitis
  • Diabetic ketoacidosis
  • Hyperlipidemia

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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