TY - JOUR
T1 - Post-operative complications following primary ACL reconstruction using allogenic and autogenic soft tissue grafts
T2 - Increased relative morbidity risk is associated with increased graft diameter
AU - Crawford, Dennis C.
AU - Hallvik, Sara E.
AU - Petering, Ryan C.
AU - Quilici, Samantha M.
AU - Black, Loren O.
AU - Lavigne, Stephanie A.
AU - Lapidus, Jodi
AU - Marshall, Lynn M.
PY - 2013/12
Y1 - 2013/12
N2 - Background: The purpose of this study is to compare the risk of peri-operative complication events associated with allogenic and autogenic grafts during routine follow-up for six months after primary arthroscopic anterior cruciate ligament (ACL) reconstruction surgery. Methods: A retrospective cohort study identified patients that underwent ACL reconstruction via an arthroscopically assisted single tunnel technique. Fixation was primarily cortical suspension (endobutton) from the femora and bicortical fixation (Washer-loc) in the tibia. Patients were monitored for six months following surgery. Morbidity was defined as complications during this period requiring medical or surgical intervention. Risk of complications was compared according to tissue type and patient characteristics. The Cochran-Mantel-Haenszel method was applied to estimate risk ratios (RR) and confidence intervals (CI) as the measure of association between graft type and morbidity risk. Results: The cohort included 413 eligible patients. Sixty six percent received allograft tissue, while the remainder received autograft tissue. Morbidity risk was 7.0% among patients receiving allograft tissue and 2.8% among patients receiving autograft tissue. Allograft demonstrated elevated risk of complication versus autograft (RR = 2.3 (95% CI: 0.9-7.2)), though the data are of borderline significance (p = 0.11). Complications were associated with larger graft diameter in comparison to patients who experienced no complication (9.0. +/- 1.2 mm v. 8.4 +/- 1.0. mm, p = 0.005). Conclusion: The relative morbidity risk was about two-fold greater among patients receiving allograft tissue. Regardless of tissue type, graft size was larger among patients who experienced a complication. Level of evidence: Level III.
AB - Background: The purpose of this study is to compare the risk of peri-operative complication events associated with allogenic and autogenic grafts during routine follow-up for six months after primary arthroscopic anterior cruciate ligament (ACL) reconstruction surgery. Methods: A retrospective cohort study identified patients that underwent ACL reconstruction via an arthroscopically assisted single tunnel technique. Fixation was primarily cortical suspension (endobutton) from the femora and bicortical fixation (Washer-loc) in the tibia. Patients were monitored for six months following surgery. Morbidity was defined as complications during this period requiring medical or surgical intervention. Risk of complications was compared according to tissue type and patient characteristics. The Cochran-Mantel-Haenszel method was applied to estimate risk ratios (RR) and confidence intervals (CI) as the measure of association between graft type and morbidity risk. Results: The cohort included 413 eligible patients. Sixty six percent received allograft tissue, while the remainder received autograft tissue. Morbidity risk was 7.0% among patients receiving allograft tissue and 2.8% among patients receiving autograft tissue. Allograft demonstrated elevated risk of complication versus autograft (RR = 2.3 (95% CI: 0.9-7.2)), though the data are of borderline significance (p = 0.11). Complications were associated with larger graft diameter in comparison to patients who experienced no complication (9.0. +/- 1.2 mm v. 8.4 +/- 1.0. mm, p = 0.005). Conclusion: The relative morbidity risk was about two-fold greater among patients receiving allograft tissue. Regardless of tissue type, graft size was larger among patients who experienced a complication. Level of evidence: Level III.
KW - ACL allograft reconstruction
KW - ACL autograft reconstruction
KW - ACL reconstruction complications
KW - Anterior cruciate ligament reconstruction
UR - http://www.scopus.com/inward/record.url?scp=84887242771&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84887242771&partnerID=8YFLogxK
U2 - 10.1016/j.knee.2013.04.013
DO - 10.1016/j.knee.2013.04.013
M3 - Article
C2 - 23665123
AN - SCOPUS:84887242771
SN - 0968-0160
VL - 20
SP - 520
EP - 525
JO - Knee
JF - Knee
IS - 6
ER -