Quantitative angioscopy: A novel method of measurement of luminal dimensions during angioscopy with the use of a "lightwire"

J. Richard Spears, Mahmood Ali, Syed J. Raza, Gayathri S. Iyer, Srihari Ravi, Richard J. Crilly, Barbara Fromm, Wai Fung Cheong

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Purpose: To determine the accuracy and reproducibility of luminal dimension measurements of a newly developed method of quantitative angioscopy. Methods: A method was developed for quantitation of luminal dimensions during angioscopy, as variation in magnification with lens-object distance and ambiguity associated with identification of corresponding points about the circumference of a given discrete cross-section render subjective estimates unreliable. A transverse ring of fiberoptically transmitted light was emitted from a guidewire or its housing at a known distance from the distal end of an angioscope and discrete cross-sections of interest were observed as the ring of light was reflected from the luminal surface. Caliper measurement of the diameter of the light ring image (< 50 mW at 488/515 nm), obtained on angioscopic video recordings of cylindrical phantom vessels of known dimensions, was performed by three observers on five occasions. Results: The mean absolute difference between measured and known luminal diameter (n = 405 observations) was 65 μm±35 μm and the mean coefficient of variation was 4.2%, and the mean difference between measured and known areas (n = 195 observations) was 0.4 mm2, with a mean coefficient of variation of 6.5%. Conclusion: By use of this new lightwire method, luminal dimensions can now be measured in vitro with a high degree of accuracy and reproducibility during angioscopy.

Original languageEnglish (US)
Pages (from-to)197-203
Number of pages7
JournalCardiovascular and interventional radiology
Issue number4
StatePublished - Jul 1994
Externally publishedYes


  • Angiography
  • Angioscopy
  • Atherosclerosis
  • Coronary artery disease

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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