Quetiapine and refractory hypotension during general anesthesia in the operating room

Katherine A. Poole; Nina Weber; Michael Aziz

doi:10.1213/ANE.0b013e3182999689

Quetiapine and refractory hypotension during general anesthesia in the operating room

Katherine A. Poole, Nina Weber, Michael Aziz

Anesthesiology and Perioperative Medicine

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Quetiapine is an atypical antipsychotic with known α-adrenergic antagonism. We present a case of refractory hypotension that occurred after induction of general anesthesia in a patient being treated with quetiapine. This patient was not currently taking antihypertensives and had no known cardiovascular abnormalities. We observed that the hypotension was most responsive to vasopressin. We recommend further investigation regarding the interaction of quetiapine and general anesthesia.

Original language	English (US)
Pages (from-to)	641-643
Number of pages	3
Journal	Anesthesia and analgesia
Volume	117
Issue number	3
DOIs	https://doi.org/10.1213/ANE.0b013e3182999689
State	Published - Sep 2013

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

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10.1213/ANE.0b013e3182999689

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abstract = "Quetiapine is an atypical antipsychotic with known α-adrenergic antagonism. We present a case of refractory hypotension that occurred after induction of general anesthesia in a patient being treated with quetiapine. This patient was not currently taking antihypertensives and had no known cardiovascular abnormalities. We observed that the hypotension was most responsive to vasopressin. We recommend further investigation regarding the interaction of quetiapine and general anesthesia.",

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AB - Quetiapine is an atypical antipsychotic with known α-adrenergic antagonism. We present a case of refractory hypotension that occurred after induction of general anesthesia in a patient being treated with quetiapine. This patient was not currently taking antihypertensives and had no known cardiovascular abnormalities. We observed that the hypotension was most responsive to vasopressin. We recommend further investigation regarding the interaction of quetiapine and general anesthesia.

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Quetiapine and refractory hypotension during general anesthesia in the operating room

Abstract

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