Radionuclide Detection of Diffuse Interstitial Pulmonary Calcification

George M. Grames; Donald D. Sauser; Carl Jansen; Robert E. Soderblom; John E. Hodgkin; Mildred S. Stilson

doi:10.1001/jama.1974.03240070026020

Radionuclide Detection of Diffuse Interstitial Pulmonary Calcification

George M. Grames, Donald D. Sauser, Carl Jansen, Robert E. Soderblom, John E. Hodgkin, Mildred S. Stilson

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

Two patients who had hypercalcemia, one from multiple myeloma and the other from metastatic carcinoma, showed striking concentrations of bone-seeking radiopharmaceuticals in the lungs on routine bone scans. Neither patient had roentgenographic evidence of intrapulmonary calcification. Histologic examination in one patient showed extensive interstitial pulmonary calcification. These cases dramatically illustrate the capability of radionuclides to detect interstitial pulmonary calcification when radiographic demonstration is lacking. The early detection of extraskeletal calcification by bone-seeking radionuclides provides a unique opportunity, not previously available, to study metastatic calcification and the effects of treatment.

Original language	English (US)
Pages (from-to)	992-995
Number of pages	4
Journal	JAMA: The Journal of the American Medical Association
Volume	230
Issue number	7
DOIs	https://doi.org/10.1001/jama.1974.03240070026020
State	Published - Nov 18 1974
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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10.1001/jama.1974.03240070026020

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abstract = "Two patients who had hypercalcemia, one from multiple myeloma and the other from metastatic carcinoma, showed striking concentrations of bone-seeking radiopharmaceuticals in the lungs on routine bone scans. Neither patient had roentgenographic evidence of intrapulmonary calcification. Histologic examination in one patient showed extensive interstitial pulmonary calcification. These cases dramatically illustrate the capability of radionuclides to detect interstitial pulmonary calcification when radiographic demonstration is lacking. The early detection of extraskeletal calcification by bone-seeking radionuclides provides a unique opportunity, not previously available, to study metastatic calcification and the effects of treatment.",

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AU - Sauser, Donald D.

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AU - Hodgkin, John E.

AU - Stilson, Mildred S.

PY - 1974/11/18

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AB - Two patients who had hypercalcemia, one from multiple myeloma and the other from metastatic carcinoma, showed striking concentrations of bone-seeking radiopharmaceuticals in the lungs on routine bone scans. Neither patient had roentgenographic evidence of intrapulmonary calcification. Histologic examination in one patient showed extensive interstitial pulmonary calcification. These cases dramatically illustrate the capability of radionuclides to detect interstitial pulmonary calcification when radiographic demonstration is lacking. The early detection of extraskeletal calcification by bone-seeking radionuclides provides a unique opportunity, not previously available, to study metastatic calcification and the effects of treatment.

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Radionuclide Detection of Diffuse Interstitial Pulmonary Calcification

Abstract

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