Recurrent second trimester pregnancy loss: Evaluation and management

Stephanie Dukhovny, Priyanka Zutshi, Jodi F. Abbott

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


Purpose of review: Recurrent pregnancy loss usually refers to first trimester losses. The present article describes the importance of a thorough evaluation for any patient presenting with a second trimester loss, and reviews current data regarding evidence-based evaluation and management for those families who have had recurrent episodes of second trimester losses. A management protocol is presented to guide management of a current pregnancy with a history of recurrent second trimester losses. Recent findings: Previous literature has focused on isolated causes of second trimester loss and management. The present review incorporates all presentations of loss into a stepwise evaluative and management paradigm. Summary: This comprehensive literature review and management protocol will provide the clinician with a thorough, systematic, and practical approach to the patient with recurrent pregnancy loss in order to maximize her chance of optimal pregnancy outcome.

Original languageEnglish (US)
Pages (from-to)451-458
Number of pages8
JournalCurrent Opinion in Endocrinology, Diabetes and Obesity
Issue number6
StatePublished - Dec 2009
Externally publishedYes


  • Cervical insufficiency
  • Fetal demise
  • Miscarriage
  • Recurrent second trimester pregnancy loss
  • Thrombophilia

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Nutrition and Dietetics


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