TY - JOUR
T1 - Regional distribution of glutamate receptor mRNA in the monkey hippocampus and temporal cortex
T2 - Influence of estradiol
AU - Kohama, Steven G.
AU - Garyfallou, Vasilios T.
AU - Urbanski, Henryk F.
N1 - Funding Information:
The authors would like to thank Shigetada Nakanishi (Kyoto University, Kyoto, Japan) and Michael Hollmann (Salk Institute, La Jolla, CA) for the donation of the NR1, GluR1 and GluR2 cDNAs, respectively. The kind assistance of Jared Cooper with tissue sectioning was also greatly appreciated. This research was supported by the Alzheimer's Association/Ogilvy and Mather Research Grant and the National Institutes of Health (HD-29186, HD-18185 and RR-00163).
PY - 1998/1
Y1 - 1998/1
N2 - The distribution of N-methyl-D-aspartate (NMDA) and α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) glutamate receptor subunits was examined in the hippocampus and temporal cortex of adult ovariectomized female rhesus macaques, some of which received estradiol replacement. In situ hybridization revealed a generalized overlap of NR1, GluR1, and GluR2 subunit mRNAs, but no effect due to estradiol treatment. However, regional differences in expression were noted for each subunit.
AB - The distribution of N-methyl-D-aspartate (NMDA) and α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) glutamate receptor subunits was examined in the hippocampus and temporal cortex of adult ovariectomized female rhesus macaques, some of which received estradiol replacement. In situ hybridization revealed a generalized overlap of NR1, GluR1, and GluR2 subunit mRNAs, but no effect due to estradiol treatment. However, regional differences in expression were noted for each subunit.
KW - AMPA
KW - In situ hybridization
KW - NMDA
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U2 - 10.1016/S0169-328X(97)00282-9
DO - 10.1016/S0169-328X(97)00282-9
M3 - Article
C2 - 9473714
AN - SCOPUS:0031932592
SN - 0169-328X
VL - 53
SP - 328
EP - 332
JO - Molecular Brain Research
JF - Molecular Brain Research
IS - 1-2
ER -