Regional therapy of high grade astrocytomas

James V. Manzione, Stefan Madajewicz, Clemente Roque, Patricia Roche, Arafat Tfayli, Maisie L. Shindo

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


High grade astrocytomas are difficult to treat surgically due to the diffuse nature of these lesions. Systemic chemotherapy has poor results due to limited penetration into the tumor and systemic toxicity. Regional therapy of high grade astrocytomas represents a promising new approach to these lesions. This article reviews recent experience with intraarterial chemotherapy in the treatment of these lesions.

Original languageEnglish (US)
Pages (from-to)365-371
Number of pages7
JournalSeminars in Interventional Radiology
Issue number4
StatePublished - 1998
Externally publishedYes


  • Astrocytomas
  • Chemotherapy
  • Regional therapy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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