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Release of interleukin-1 by peripheral blood mononuclear cells in patients with tuberculosis and active inflammation

  • S. W. Chensue
  • , M. P. Davey
  • , D. G. Remick
  • , S. L. Kunkel

Research output: Contribution to journalArticlepeer-review

Abstract

Peripheral blood monocytes from patients with active tuberculosis and acute inflammatory disease showed spontaneous interleukin-1 production when compared with those from control patients or healthy controls. Moreover, interleukin-1 production appeared to be a more specific indicator of active disease than were other commonly used indices, such as the erythrocyte sedimentation rate and serum C-reactive protein levels.

Original languageEnglish (US)
Pages (from-to)341-343
Number of pages3
JournalInfection and Immunity
Volume52
Issue number1
DOIs
StatePublished - 1986
Externally publishedYes

Funding

FundersFunder number
National Institute of Health National Heart, Lung, and Blood InstituteR01HL031237

    ASJC Scopus subject areas

    • Parasitology
    • Microbiology
    • Immunology
    • Infectious Diseases

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