Renal Function During Neurolept Anaesthesia

Per‐Olof ‐O Järnberg, Joakim Santesson, Jan Eklund

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Renal function and central haemodynamics were studied in eight patients, without known histories of renal or cardiovascular disease, during and immediately after upper abdominal surgery under neurolept anaesthesia. Inulin and PAH clearance, fractional sodium and fractional osmolal excretion decreased, while fractional free water reabsorption increased under anaesthesia. Cardiac output, mean systemic arterial pressure and systemic vascular resistance remained virtually unchanged both per‐ and postoperatively. Renal haemodynamics were promptly restored postoperatively, while fractional sodium and fractional osmolal excretion were unaltered and antidiuresis increased. It is concluded that neurolept anaesthesia, as far as renal function is concerned, is well suited for the anaesthetic management of the poor‐risk patient.

Original languageEnglish (US)
Pages (from-to)167-172
Number of pages6
JournalActa Anaesthesiologica Scandinavica
Issue number2
StatePublished - Apr 1978
Externally publishedYes

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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