Response to Hron et al.

Peter V. Lovell; Morgan Wirthlin; Lucia Carbone; Wesley C. Warren; Claudio V. Mello

doi:10.1186/s13059-015-0725-y

Response to Hron et al.

Peter V. Lovell, Morgan Wirthlin, Lucia Carbone, Wesley C. Warren, Claudio V. Mello

Research output: Contribution to journal › Letter › peer-review

10 Scopus citations

Abstract

Hron et al. provide transcriptome evidence that three (1.1 %) of the 274 genes reported by Lovell et al. as missing in birds may actually be 'hidden' as a result of high GC content. Although this factor may explain some gene absences from genomic assemblies, we believe it is insufficient to account for the extensive syntenic losses described in Lovell et al.

Original language	English (US)
Article number	165
Journal	Genome biology
Volume	16
Issue number	1
DOIs	https://doi.org/10.1186/s13059-015-0725-y
State	Published - Aug 18 2015

Keywords

Gene loss
Gene loss
Genome assembly
Synteny verification

ASJC Scopus subject areas

Ecology, Evolution, Behavior and Systematics
Genetics
Cell Biology

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10.1186/s13059-015-0725-y

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title = "Response to Hron et al.",

abstract = "Hron et al. provide transcriptome evidence that three (1.1 %) of the 274 genes reported by Lovell et al. as missing in birds may actually be 'hidden' as a result of high GC content. Although this factor may explain some gene absences from genomic assemblies, we believe it is insufficient to account for the extensive syntenic losses described in Lovell et al.",

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author = "Lovell, {Peter V.} and Morgan Wirthlin and Lucia Carbone and Warren, {Wesley C.} and Mello, {Claudio V.}",

note = "Publisher Copyright: {\textcopyright} 2015 Lovell et al.",

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AU - Lovell, Peter V.

AU - Wirthlin, Morgan

AU - Carbone, Lucia

AU - Warren, Wesley C.

AU - Mello, Claudio V.

PY - 2015/8/18

Y1 - 2015/8/18

N2 - Hron et al. provide transcriptome evidence that three (1.1 %) of the 274 genes reported by Lovell et al. as missing in birds may actually be 'hidden' as a result of high GC content. Although this factor may explain some gene absences from genomic assemblies, we believe it is insufficient to account for the extensive syntenic losses described in Lovell et al.

AB - Hron et al. provide transcriptome evidence that three (1.1 %) of the 274 genes reported by Lovell et al. as missing in birds may actually be 'hidden' as a result of high GC content. Although this factor may explain some gene absences from genomic assemblies, we believe it is insufficient to account for the extensive syntenic losses described in Lovell et al.

KW - Gene loss

KW - Genome assembly

KW - Synteny verification

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ER -

Response to Hron et al.

Abstract

Keywords

ASJC Scopus subject areas

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