Role of (p)ppGpp in biofilm formation by Enterococcus faecalis

Luis E. Chávez de Paz, José A. Lemos, Claes Wickström, Christine M. Sedgley

Research output: Contribution to journalArticlepeer-review

52 Scopus citations


Enterococcus faecalis strain OG1RF and its (p)ppGpp-deficient ΔrelA, ΔrelQ, and ΔrelA ΔrelQ mutants were grown in biofilms and evaluated for growth profiles, biofilm morphology, cell viability, and proteolytic activity. E. faecalis lacking (p)ppGpp had a diminished capacity to sustain biofilm formation over an extended period of time and expressed abundant proteolytic activity.

Original languageEnglish (US)
Pages (from-to)1627-1630
Number of pages4
JournalApplied and Environmental Microbiology
Issue number5
StatePublished - Mar 2012
Externally publishedYes

ASJC Scopus subject areas

  • Biotechnology
  • Food Science
  • Applied Microbiology and Biotechnology
  • Ecology


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