TY - JOUR
T1 - Role of (p)ppGpp in biofilm formation by Enterococcus faecalis
AU - Chávez de Paz, Luis E.
AU - Lemos, José A.
AU - Wickström, Claes
AU - Sedgley, Christine M.
PY - 2012/3
Y1 - 2012/3
N2 - Enterococcus faecalis strain OG1RF and its (p)ppGpp-deficient ΔrelA, ΔrelQ, and ΔrelA ΔrelQ mutants were grown in biofilms and evaluated for growth profiles, biofilm morphology, cell viability, and proteolytic activity. E. faecalis lacking (p)ppGpp had a diminished capacity to sustain biofilm formation over an extended period of time and expressed abundant proteolytic activity.
AB - Enterococcus faecalis strain OG1RF and its (p)ppGpp-deficient ΔrelA, ΔrelQ, and ΔrelA ΔrelQ mutants were grown in biofilms and evaluated for growth profiles, biofilm morphology, cell viability, and proteolytic activity. E. faecalis lacking (p)ppGpp had a diminished capacity to sustain biofilm formation over an extended period of time and expressed abundant proteolytic activity.
UR - http://www.scopus.com/inward/record.url?scp=84857077963&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84857077963&partnerID=8YFLogxK
U2 - 10.1128/AEM.07036-11
DO - 10.1128/AEM.07036-11
M3 - Article
C2 - 22179256
AN - SCOPUS:84857077963
SN - 0099-2240
VL - 78
SP - 1627
EP - 1630
JO - Applied and Environmental Microbiology
JF - Applied and Environmental Microbiology
IS - 5
ER -