Role of (p)ppGpp in biofilm formation by Enterococcus faecalis

Luis E. Chávez de Paz; José A. Lemos; Claes Wickström; Christine M. Sedgley

doi:10.1128/AEM.07036-11

Role of (p)ppGpp in biofilm formation by Enterococcus faecalis

Luis E. Chávez de Paz, José A. Lemos, Claes Wickström, Christine M. Sedgley

Research output: Contribution to journal › Article › peer-review

52 Scopus citations

Abstract

Enterococcus faecalis strain OG1RF and its (p)ppGpp-deficient ΔrelA, ΔrelQ, and ΔrelA ΔrelQ mutants were grown in biofilms and evaluated for growth profiles, biofilm morphology, cell viability, and proteolytic activity. E. faecalis lacking (p)ppGpp had a diminished capacity to sustain biofilm formation over an extended period of time and expressed abundant proteolytic activity.

Original language	English (US)
Pages (from-to)	1627-1630
Number of pages	4
Journal	Applied and Environmental Microbiology
Volume	78
Issue number	5
DOIs	https://doi.org/10.1128/AEM.07036-11
State	Published - Mar 2012
Externally published	Yes

ASJC Scopus subject areas

Biotechnology
Food Science
Applied Microbiology and Biotechnology
Ecology

Access to Document

10.1128/AEM.07036-11

Cite this

@article{48594c10772d458694bd1d64649ad264,

title = "Role of (p)ppGpp in biofilm formation by Enterococcus faecalis",

abstract = "Enterococcus faecalis strain OG1RF and its (p)ppGpp-deficient ΔrelA, ΔrelQ, and ΔrelA ΔrelQ mutants were grown in biofilms and evaluated for growth profiles, biofilm morphology, cell viability, and proteolytic activity. E. faecalis lacking (p)ppGpp had a diminished capacity to sustain biofilm formation over an extended period of time and expressed abundant proteolytic activity.",

author = "{Ch{\'a}vez de Paz}, {Luis E.} and Lemos, {Jos{\'e} A.} and Claes Wickstr{\"o}m and Sedgley, {Christine M.}",

year = "2012",

month = mar,

doi = "10.1128/AEM.07036-11",

language = "English (US)",

volume = "78",

pages = "1627--1630",

journal = "Applied and Environmental Microbiology",

issn = "0099-2240",

publisher = "American Society for Microbiology",

number = "5",

}

TY - JOUR

T1 - Role of (p)ppGpp in biofilm formation by Enterococcus faecalis

AU - Chávez de Paz, Luis E.

AU - Lemos, José A.

AU - Wickström, Claes

AU - Sedgley, Christine M.

PY - 2012/3

Y1 - 2012/3

N2 - Enterococcus faecalis strain OG1RF and its (p)ppGpp-deficient ΔrelA, ΔrelQ, and ΔrelA ΔrelQ mutants were grown in biofilms and evaluated for growth profiles, biofilm morphology, cell viability, and proteolytic activity. E. faecalis lacking (p)ppGpp had a diminished capacity to sustain biofilm formation over an extended period of time and expressed abundant proteolytic activity.

AB - Enterococcus faecalis strain OG1RF and its (p)ppGpp-deficient ΔrelA, ΔrelQ, and ΔrelA ΔrelQ mutants were grown in biofilms and evaluated for growth profiles, biofilm morphology, cell viability, and proteolytic activity. E. faecalis lacking (p)ppGpp had a diminished capacity to sustain biofilm formation over an extended period of time and expressed abundant proteolytic activity.

UR - http://www.scopus.com/inward/record.url?scp=84857077963&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84857077963&partnerID=8YFLogxK

U2 - 10.1128/AEM.07036-11

DO - 10.1128/AEM.07036-11

M3 - Article

C2 - 22179256

AN - SCOPUS:84857077963

SN - 0099-2240

VL - 78

SP - 1627

EP - 1630

JO - Applied and Environmental Microbiology

JF - Applied and Environmental Microbiology

IS - 5

ER -

Role of (p)ppGpp in biofilm formation by Enterococcus faecalis

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this