Scarring and scarless wound healing

B. J. Larson; A. Nauta; K. Kawai; M. T. Longaker; H. P. Lorenz

doi:10.1533/9780857093301.1.77

Scarring and scarless wound healing

B. J. Larson, A. Nauta, K. Kawai, M. T. Longaker, H. P. Lorenz

Research output: Chapter in Book/Report/Conference proceeding › Chapter

4 Scopus citations

Abstract

In contrast to adult wound healing, the early-gestation fetus has the remarkable ability to heal skin wounds without scar formation. Over the past several decades, an intensive research effort has greatly increased our understanding of scarless fetal wound healing. This chapter discusses the differences that exist between the extracellular matrix (ECM), inflammatory response, cellular mediators, stem cell function, and gene expression profiles of fetal and postnatal wounds. This chapter then reviews the currently available treatment options for scars and concludes with a discussion of future trends in scar treatment.

Original language	English (US)
Title of host publication	Advanced Wound Repair Therapies
Publisher	Elsevier Inc.
Pages	77-111
Number of pages	35
ISBN (Print)	9781845697006
DOIs	https://doi.org/10.1533/9780857093301.1.77
State	Published - Jun 2011
Externally published	Yes

Keywords

Fetal wound repair
Review
Scarless wound healing
Skin development
Wound healing

ASJC Scopus subject areas

General Dentistry
General Medicine

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10.1533/9780857093301.1.77

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title = "Scarring and scarless wound healing",

abstract = "In contrast to adult wound healing, the early-gestation fetus has the remarkable ability to heal skin wounds without scar formation. Over the past several decades, an intensive research effort has greatly increased our understanding of scarless fetal wound healing. This chapter discusses the differences that exist between the extracellular matrix (ECM), inflammatory response, cellular mediators, stem cell function, and gene expression profiles of fetal and postnatal wounds. This chapter then reviews the currently available treatment options for scars and concludes with a discussion of future trends in scar treatment.",

keywords = "Fetal wound repair, Review, Scarless wound healing, Skin development, Wound healing",

author = "Larson, {B. J.} and A. Nauta and K. Kawai and Longaker, {M. T.} and Lorenz, {H. P.}",

year = "2011",

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language = "English (US)",

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TY - CHAP

T1 - Scarring and scarless wound healing

AU - Larson, B. J.

AU - Nauta, A.

AU - Kawai, K.

AU - Longaker, M. T.

AU - Lorenz, H. P.

PY - 2011/6

Y1 - 2011/6

N2 - In contrast to adult wound healing, the early-gestation fetus has the remarkable ability to heal skin wounds without scar formation. Over the past several decades, an intensive research effort has greatly increased our understanding of scarless fetal wound healing. This chapter discusses the differences that exist between the extracellular matrix (ECM), inflammatory response, cellular mediators, stem cell function, and gene expression profiles of fetal and postnatal wounds. This chapter then reviews the currently available treatment options for scars and concludes with a discussion of future trends in scar treatment.

AB - In contrast to adult wound healing, the early-gestation fetus has the remarkable ability to heal skin wounds without scar formation. Over the past several decades, an intensive research effort has greatly increased our understanding of scarless fetal wound healing. This chapter discusses the differences that exist between the extracellular matrix (ECM), inflammatory response, cellular mediators, stem cell function, and gene expression profiles of fetal and postnatal wounds. This chapter then reviews the currently available treatment options for scars and concludes with a discussion of future trends in scar treatment.

KW - Fetal wound repair

KW - Review

KW - Scarless wound healing

KW - Skin development

KW - Wound healing

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DO - 10.1533/9780857093301.1.77

M3 - Chapter

AN - SCOPUS:84902046373

SN - 9781845697006

SP - 77

EP - 111

BT - Advanced Wound Repair Therapies

PB - Elsevier Inc.

ER -

Scarring and scarless wound healing

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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