Sensorimotor peripheral nerve function and physical activity in older men

Brittney S. Lange-Maia; Jane A. Cauley; Anne B. Newman; Robert M. Boudreau; John M. Jakicic; Nancy W. Glynn; Sasa Zivkovic; Thuy Tien L. Dam; Paolo Caserotti; Peggy M. Cawthon; Eric S. Orwoll; Elsa S. Strotmeyer

doi:10.1123/japa.2015-0207

Sensorimotor peripheral nerve function and physical activity in older men

Brittney S. Lange-Maia, Jane A. Cauley, Anne B. Newman, Robert M. Boudreau, John M. Jakicic, Nancy W. Glynn, Sasa Zivkovic, Thuy Tien L. Dam, Paolo Caserotti, Peggy M. Cawthon, Eric S. Orwoll, Elsa S. Strotmeyer

Endocrinology, Diabetes and Clinical Nutrition

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

We determined whether sensorimotor peripheral nerve (PN) function was associated with physical activity (PA) in older men. The Osteoporotic Fractures in Men Study Pittsburgh, PA, site (n = 328, age 78.8 ± 4.7 years) conducted PN testing, including: peroneal motor and sural sensory nerve conduction (latencies, amplitudes: CMAP and SNAP for motor and sensory amplitude, respectively), 1.4g/10g monoflament (dorsum of the great toe), and neuropathy symptoms. ANOVA and multivariate linear regression modeled PN associations with PA (Physical Activity Scale for the Elderly [PASE] and SenseWear Armband). After multivariable adjustment, better motor latency was associated with higher PASE scores (160.5 ± 4.8 vs. 135.6 ± 6.7, p <.01). Those without versus with neuropathy symptoms had higher PASE scores (157.6 ± 5.3 vs. 132.9 ± 7.1, p <.01). Better versus worse SNAP was associated with slightly more daily vigorous activity (9.5 ± 0.8 vs. 7.3 ± 0.7, p =.05). Other PN measures were not associated with PA. Certain PN measures were associated with lower PA, suggesting a potential pathway for disability.

Original language	English (US)
Pages (from-to)	559-566
Number of pages	8
Journal	Journal of Aging and Physical Activity
Volume	24
Issue number	4
DOIs	https://doi.org/10.1123/japa.2015-0207
State	Published - Oct 2016

Keywords

Aging
Motor peripheral nerve
Sensory peripheral nerve

ASJC Scopus subject areas

Physical Therapy, Sports Therapy and Rehabilitation
Rehabilitation
Gerontology
Geriatrics and Gerontology

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title = "Sensorimotor peripheral nerve function and physical activity in older men",

abstract = "We determined whether sensorimotor peripheral nerve (PN) function was associated with physical activity (PA) in older men. The Osteoporotic Fractures in Men Study Pittsburgh, PA, site (n = 328, age 78.8 ± 4.7 years) conducted PN testing, including: peroneal motor and sural sensory nerve conduction (latencies, amplitudes: CMAP and SNAP for motor and sensory amplitude, respectively), 1.4g/10g monoflament (dorsum of the great toe), and neuropathy symptoms. ANOVA and multivariate linear regression modeled PN associations with PA (Physical Activity Scale for the Elderly [PASE] and SenseWear Armband). After multivariable adjustment, better motor latency was associated with higher PASE scores (160.5 ± 4.8 vs. 135.6 ± 6.7, p <.01). Those without versus with neuropathy symptoms had higher PASE scores (157.6 ± 5.3 vs. 132.9 ± 7.1, p <.01). Better versus worse SNAP was associated with slightly more daily vigorous activity (9.5 ± 0.8 vs. 7.3 ± 0.7, p =.05). Other PN measures were not associated with PA. Certain PN measures were associated with lower PA, suggesting a potential pathway for disability.",

keywords = "Aging, Motor peripheral nerve, Sensory peripheral nerve",

author = "Lange-Maia, {Brittney S.} and Cauley, {Jane A.} and Newman, {Anne B.} and Boudreau, {Robert M.} and Jakicic, {John M.} and Glynn, {Nancy W.} and Sasa Zivkovic and Dam, {Thuy Tien L.} and Paolo Caserotti and Cawthon, {Peggy M.} and Orwoll, {Eric S.} and Strotmeyer, {Elsa S.}",

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AU - Lange-Maia, Brittney S.

AU - Cauley, Jane A.

AU - Newman, Anne B.

AU - Boudreau, Robert M.

AU - Jakicic, John M.

AU - Glynn, Nancy W.

AU - Zivkovic, Sasa

AU - Dam, Thuy Tien L.

AU - Caserotti, Paolo

AU - Cawthon, Peggy M.

AU - Orwoll, Eric S.

AU - Strotmeyer, Elsa S.

PY - 2016/10

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N2 - We determined whether sensorimotor peripheral nerve (PN) function was associated with physical activity (PA) in older men. The Osteoporotic Fractures in Men Study Pittsburgh, PA, site (n = 328, age 78.8 ± 4.7 years) conducted PN testing, including: peroneal motor and sural sensory nerve conduction (latencies, amplitudes: CMAP and SNAP for motor and sensory amplitude, respectively), 1.4g/10g monoflament (dorsum of the great toe), and neuropathy symptoms. ANOVA and multivariate linear regression modeled PN associations with PA (Physical Activity Scale for the Elderly [PASE] and SenseWear Armband). After multivariable adjustment, better motor latency was associated with higher PASE scores (160.5 ± 4.8 vs. 135.6 ± 6.7, p <.01). Those without versus with neuropathy symptoms had higher PASE scores (157.6 ± 5.3 vs. 132.9 ± 7.1, p <.01). Better versus worse SNAP was associated with slightly more daily vigorous activity (9.5 ± 0.8 vs. 7.3 ± 0.7, p =.05). Other PN measures were not associated with PA. Certain PN measures were associated with lower PA, suggesting a potential pathway for disability.

AB - We determined whether sensorimotor peripheral nerve (PN) function was associated with physical activity (PA) in older men. The Osteoporotic Fractures in Men Study Pittsburgh, PA, site (n = 328, age 78.8 ± 4.7 years) conducted PN testing, including: peroneal motor and sural sensory nerve conduction (latencies, amplitudes: CMAP and SNAP for motor and sensory amplitude, respectively), 1.4g/10g monoflament (dorsum of the great toe), and neuropathy symptoms. ANOVA and multivariate linear regression modeled PN associations with PA (Physical Activity Scale for the Elderly [PASE] and SenseWear Armband). After multivariable adjustment, better motor latency was associated with higher PASE scores (160.5 ± 4.8 vs. 135.6 ± 6.7, p <.01). Those without versus with neuropathy symptoms had higher PASE scores (157.6 ± 5.3 vs. 132.9 ± 7.1, p <.01). Better versus worse SNAP was associated with slightly more daily vigorous activity (9.5 ± 0.8 vs. 7.3 ± 0.7, p =.05). Other PN measures were not associated with PA. Certain PN measures were associated with lower PA, suggesting a potential pathway for disability.

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KW - Sensory peripheral nerve

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Sensorimotor peripheral nerve function and physical activity in older men

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