Sertraline-Associated Cholestasis and Ductopenia Consistent with Vanishing Bile Duct Syndrome

Máire A. Conrad, Jiawei Cui, Henry C. Lin

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


An adolescent with depression treated with sertraline developed cholestasis and bile duct paucity, which resolved with medication discontinuation. Vanishing bile duct syndrome is an acquired destruction of interlobular bile ducts. This type of drug-induced liver injury has been associated with other medications and requires practitioners' awareness of potential hepatotoxicity.

Original languageEnglish (US)
Pages (from-to)313-315.e1
JournalJournal of Pediatrics
StatePublished - Feb 1 2016
Externally publishedYes


  • Dili Drug-induced liver injury
  • SSRI Selective serotonin reuptake inhibitor
  • VBDS Vanishing bile duct syndrome

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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