Sex differences in prefrontal volume with aging and Alzheimer's disease

D. H. Salat; P. A. Stangl; J. A. Kaye; J. S. Janowsky

doi:10.1016/S0197-4580(99)00067-6

Sex differences in prefrontal volume with aging and Alzheimer's disease

D. H. Salat, P. A. Stangl, J. A. Kaye, J. S. Janowsky

Neurology

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

We used volumetric magnetic resonance imaging to examine sex differences in prefrontal tissue volumes of healthy aged and patients with Alzheimer's disease (AD). Healthy subjects had greater total prefrontal volume than AD, and men had greater total prefrontal volume than women (ps ≤ 0.02). This was true for both gray and white matter volumes. There were no interactions between group and sex for total prefrontal volume. An exploratory analysis of each group suggested that sex differences in both gray and white matter in healthy aging are not sustained in AD. Copyright (C) 1999 Elsevier Science Inc.

Original language	English (US)
Pages (from-to)	591-596
Number of pages	6
Journal	Neurobiology of Aging
Volume	20
Issue number	6
DOIs	https://doi.org/10.1016/S0197-4580(99)00067-6
State	Published - Nov 1999

Keywords

Aged
Aging
Alzheimer's disease
Frontal lobe
Gray matter
Human
Magnetic resonance imaging
Prefrontal
Sex characteristics

ASJC Scopus subject areas

Neuroscience(all)
Aging
Clinical Neurology
Developmental Biology
Geriatrics and Gerontology

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10.1016/S0197-4580(99)00067-6

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AU - Stangl, P. A.

AU - Kaye, J. A.

AU - Janowsky, J. S.

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KW - Alzheimer's disease

KW - Frontal lobe

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KW - Sex characteristics

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Sex differences in prefrontal volume with aging and Alzheimer's disease

Abstract

Keywords

ASJC Scopus subject areas

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