Abstract
In cancer, complex ecosystems of interacting cell types play fundamental roles in tumor development, progression, and response to therapy. However, the cellular organization, community structure, and spatially defined microenvironments of human tumors remain poorly understood. With the emergence of new technologies for high-throughput spatial profiling of complex tissue specimens, it is now possible to identify clinically significant spatial features with high granularity. In this PSB workshop, we will highlight recent advances in this area and explore how single cell spatial profiling can advance precision cancer medicine.
Original language | English (US) |
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Pages (from-to) | 549-553 |
Number of pages | 5 |
Journal | Pacific Symposium on Biocomputing |
Issue number | 2023 |
DOIs | |
State | Published - 2023 |
Event | 28th Pacific Symposium on Biocomputing, PSB 2023 - Kohala Coast, United States Duration: Jan 3 2023 → Jan 7 2023 |
Keywords
- Spatial biology
- artificial intelligence
- cancer biology
- machine learning
- precision medicine
- spatial transcriptomics
ASJC Scopus subject areas
- Biomedical Engineering
- Computational Theory and Mathematics