St. John: Not such a saint: Fatal Forty DDI: St. John's wort, cyclosporine, CYP3A4, P-glycoprotein

Heather Norvelle; Ines P. Koerner

doi:10.1007/978-1-4614-7495-1_219

St. John: Not such a saint: Fatal Forty DDI: St. John's wort, cyclosporine, CYP3A4, P-glycoprotein

Heather Norvelle, Ines P. Koerner

Anesthesiology and Perioperative Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This case discusses the pharmacokinetic interaction between cyclosporine and St. John's wort, resulting in renal failure. Cylcosporin is a cytochrome P450 3A4 and P-glycoprotein substrate and St. John's wort is a 3A4 and P-glycoprotein inducer.

Original language	English (US)
Title of host publication	A Case Approach to Perioperative Drug-Drug Interactions
Publisher	Springer New York
Pages	969-971
Number of pages	3
ISBN (Electronic)	9781461474951
ISBN (Print)	9781461474944
DOIs	https://doi.org/10.1007/978-1-4614-7495-1_219
State	Published - Sep 15 2015

ASJC Scopus subject areas

Medicine(all)

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10.1007/978-1-4614-7495-1_219

Cite this

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abstract = "This case discusses the pharmacokinetic interaction between cyclosporine and St. John's wort, resulting in renal failure. Cylcosporin is a cytochrome P450 3A4 and P-glycoprotein substrate and St. John's wort is a 3A4 and P-glycoprotein inducer.",

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AB - This case discusses the pharmacokinetic interaction between cyclosporine and St. John's wort, resulting in renal failure. Cylcosporin is a cytochrome P450 3A4 and P-glycoprotein substrate and St. John's wort is a 3A4 and P-glycoprotein inducer.

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St. John: Not such a saint: Fatal Forty DDI: St. John's wort, cyclosporine, CYP3A4, P-glycoprotein

Abstract

ASJC Scopus subject areas

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