TY - JOUR
T1 - State of the Science
T2 - The Relevance of Symptoms in Cardiovascular Disease and Research: A Scientific Statement from the American Heart Association
AU - Jurgens, Corrine Y.
AU - Lee, Christopher
AU - Aycock, Dawn M.
AU - Masterson Creber, Ruth
AU - Denfeld, Quin E.
AU - Devon, Holli A.
AU - Evers, Linda R.
AU - Jung, Miyeon
AU - Pucciarelli, Gianluca
AU - Streur, Megan M.
AU - Konstam, Marvin A.
N1 - Publisher Copyright:
© 2022 Lippincott Williams and Wilkins. All rights reserved.
PY - 2022/9/20
Y1 - 2022/9/20
N2 - Symptoms of cardiovascular disease drive health care use and are a major contributor to quality of life. Symptoms are of fundamental significance not only to the diagnosis of cardiovascular disease and appraisal of response to medical therapy but also directly to patients' daily lives. The primary purpose of this scientific statement is to present the state of the science and relevance of symptoms associated with cardiovascular disease. Symptoms as patient-reported outcomes are reviewed in terms of the genesis, manifestation, and similarities or differences between diagnoses. Specifically, symptoms associated with acute coronary syndrome, heart failure, valvular disorders, stroke, rhythm disorders, and peripheral vascular disease are reviewed. Secondary aims include (1) describing symptom measurement methods in research and application in clinical practice and (2) describing the importance of cardiovascular disease symptoms in terms of clinical events and other patient-reported outcomes as applicable.
AB - Symptoms of cardiovascular disease drive health care use and are a major contributor to quality of life. Symptoms are of fundamental significance not only to the diagnosis of cardiovascular disease and appraisal of response to medical therapy but also directly to patients' daily lives. The primary purpose of this scientific statement is to present the state of the science and relevance of symptoms associated with cardiovascular disease. Symptoms as patient-reported outcomes are reviewed in terms of the genesis, manifestation, and similarities or differences between diagnoses. Specifically, symptoms associated with acute coronary syndrome, heart failure, valvular disorders, stroke, rhythm disorders, and peripheral vascular disease are reviewed. Secondary aims include (1) describing symptom measurement methods in research and application in clinical practice and (2) describing the importance of cardiovascular disease symptoms in terms of clinical events and other patient-reported outcomes as applicable.
KW - AHA Scientific Statements
KW - arrhythmias
KW - cardiovascular disease
KW - coronary artery disease
KW - heart failure
KW - patient-reported outcomes
KW - peripheral vascular disease
KW - stroke
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U2 - 10.1161/CIR.0000000000001089
DO - 10.1161/CIR.0000000000001089
M3 - Review article
C2 - 35979825
AN - SCOPUS:85138457855
SN - 0009-7322
VL - 146
SP - E173-E184
JO - Circulation
JF - Circulation
IS - 12
ER -