Abstract
A myriad of musculoskeletal conditions afflicts a vast number of the world's population from birth to death. Countless pathological diseases and traumatic injuries (acute and chronic) contribute to different human disabilities, causing a tremendous financial toll on the economy of healthcare. The medical field is continually searching for novel ways to combat orthopedically related conditions. The immediate goal is the restoration of anatomy then ultimately return of function in hopes of enhancing quality if not the quantity of life. Traditional methods involve surgical correction/reconstruction of skeletal deformities from fractures/soft tissue damage/ruptures or replacement/resection of degenerated joints. Modern research is currently concentrating on innovative procedures to replenish/restore the human body close to its original/natural state [1, 2].
| Original language | English (US) |
|---|---|
| Article number | 165624 |
| Journal | Biochimica et Biophysica Acta - Molecular Basis of Disease |
| Volume | 1866 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 1 2020 |
Funding
I would like to thank the following individuals for their prompt/expert assistance with this article: Kyla Petrie, MS2 in compiling the reference list; Aiswayra Pillai for illustrations & Mark Welborn for finalizing captions/figures.
Keywords
- Biomarkers
- Clinical trials
- Musculoskeletal disorders
- Orthopedic sports medicine
- Regenerative medicine
- Sex/gender
- Stem cells
- Tissue engineering
ASJC Scopus subject areas
- Molecular Medicine
- Molecular Biology
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