Structure and regulation of calcium/calmodulin-dependent protein kinases

Thomas R. Soderling, James T. Stull

Research output: Contribution to journalReview articlepeer-review

168 Scopus citations


The structure and regulation of calcium\calmodulin-dependent protein kinases (CaM-K) were discussed. The CaM-K were activated and inhibited through phosphorylation by other protein kinases. The results showed that the cross-talk with other signalling pathways allowed the integration of Ca2+ signals with other signalling pathways to modulate the physiological output of the cell.

Original languageEnglish (US)
Pages (from-to)2341-2351
Number of pages11
JournalChemical Reviews
Issue number8
StatePublished - Aug 2001
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)


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