Surgical management of early and late ureteral complications after renal transplantation: Techniques and outcomes

Jens U. Berli, John R. Montgomery, Dorry L. Segev, Lloyd E. Ratner, Warren R. Maley, Matthew Cooper, Joseph K. Melancon, James Burdick, Niraj M. Desai, Nabil N. Dagher, Bonnie E. Lonze, Susanna M. Nazarian, Robert A. Montgomery

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


Background: In this study, we present our experience with ureteral complications requiring revision surgery after renal transplantation and compare our results to a matched control population. Methods: We performed a retrospective analysis of our database between 1997 and 2012. We divided the cases into early (<60 d) and late repairs. Kaplan-Meier and Cox proportional hazards models were used to compare graft survival between the intervention cohort and controls generated from the Scientific Registry of Transplant Recipients data set. Results: Of 2671 kidney transplantations, 51 patients were identified as to having undergone 53 ureteral revision procedures; 43.4% of cases were performed within 60 d of the transplant and were all associated with urinary leaks, and 49% demonstrated ureteral stenosis. Reflux allograft pyelonephritis and ureterolithiasis were each the indication for intervention in 3.8%; 15.1% of the lesions were located at the anastomotic site, 37.7% in the distal segment, 7.5% in the middle segment, 5.7% proximal ureter, and 15.1% had a long segmental stenosis. In 18.9%, the location was not specified. Techniques used included ureterocystostomy (30.2%), ureteroureterostomy (34%), ureteropyelostomy (30.1%), pyeloileostomy (1.9%), and ureteroileostomy (3.8%). No difference in overall graft survival (HR 1.24 95% CI 0.33-4.64, p = 0.7) was detected when compared to the matched control group. Conclusion: Using a variety of techniques designed to re-establish effective urinary flow, we have been able to salvage a high percentage of these allografts. When performed by an experienced team, a ureteric complication does not significantly impact graft survival or function as compared to a matched control group.

Original languageEnglish (US)
Pages (from-to)26-33
Number of pages8
JournalClinical Transplantation
Issue number1
StatePublished - Jan 1 2015
Externally publishedYes


  • Renal transplantation
  • Ureteral complications
  • Ureteral leak
  • Ureteral revision
  • Ureteral stenosis

ASJC Scopus subject areas

  • Transplantation


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