TY - JOUR
T1 - Taking the Next Steps in Regenerative Rehabilitation
T2 - Establishment of a New Interdisciplinary Field
AU - Willett, Nick J.
AU - Boninger, Michael L.
AU - Miller, Laura J.
AU - Alvarez, Luis
AU - Aoyama, Tomoki
AU - Bedoni, Marzia
AU - Brix, Kelley Ann
AU - Chisari, Carmelo
AU - Christ, George
AU - Dearth, Christopher L.
AU - Dyson-Hudson, Trevor A.
AU - Evans, Christopher H.
AU - Goldman, Stephen M.
AU - Gregory, Kenton
AU - Gualerzi, Alice
AU - Hart, Joseph
AU - Ito, Akira
AU - Kuroki, Hiroshi
AU - Loghmani, M. Terry
AU - Mack, David L.
AU - Malanga, Gerard A.
AU - Noble-Haeusslein, Linda
AU - Pasquina, Paul
AU - Roche, Joseph A.
AU - Rose, Lloyd
AU - Stoddart, Martin J.
AU - Tajino, Junichi
AU - Terzic, Carmen
AU - Topp, Kimberly S.
AU - Wagner, William R.
AU - Warden, Stuart J.
AU - Wolf, Steven L.
AU - Xie, Hua
AU - Rando, Thomas A.
AU - Ambrosio, Fabrisia
N1 - Funding Information:
Supported in part by the Alliance for Regenerative Rehabilitation Research and Training (grant no. P2CHD086843; Ambrosio/Rando) and the National Institutes of Health.
Funding Information:
Kessler Foundation, in partnership with New Jersey Regenerative Institute, Kessler Institute for Rehabilitation, and the Department of Physical Medicine and Rehabilitation (PM&R) at Rutgers New Jersey Medical School has added a Regenerative Rehabilitation Fellowship to its Rehabilitation Research Training Program. The overall purpose of the postdoctoral fellowship training program is to train individuals in clinical research with the goal of improving rehabilitation outcomes for individuals with neurologic (eg, spinal cord injury, traumatic brain injury, multiple sclerosis, stroke, etc) and physical impairments. The Regenerative Rehabilitation Fellowship itself focuses on integrating regenerative medicine and rehabilitation sciences principles and practices—training that will facilitate pursuit of a career in regenerative rehabilitation research. The fellow splits time between an active rehabilitation research program and a sports medicine clinic specializing in regenerative and orthobiologic treatments. One of the goals of the fellowship is to facilitate clinically-based research on the effectiveness of various regenerative and orthobiological treatments, such as platelet rich plasma, bone marrow, and microfragmented adipose tissue, and to establish a centralized database to record treatment outcomes from other clinics performing orthobiologic treatments. The fellow participates in resident and research fellowship didactics courses offered through the PM&R department. Training and travel funds are also budgeted to encourage travel to national regenerative medicine and rehabilitation medicine conferences and training programs specializing in basic science and clinical regenerative medicine techniques. The first Regenerative Rehabilitation postdoctoral fellow was added in 2018 through a grant from the Derfner Foundation and has already yielded several published abstracts, peer-reviewed publications, and additional research grants. The fellow has also served as a research mentor to many of the PM&R residents, who are required to do a research project as part of their residency training program. Given the success of the Regenerative Rehabilitation fellowship, the goal is to expand the fellowship program with the addition of new fellows and to continue to expand the regenerative rehabilitation research partnership between Kessler Foundation and New Jersey Regenerative Institute, as well as other outside collaborators.
Funding Information:
Supported in part by the Alliance for Regenerative Rehabilitation Research and Training (grant no. P2CHD086843; Ambrosio/Rando) and the National Institutes of Health .
Publisher Copyright:
© 2020
PY - 2020/5
Y1 - 2020/5
N2 - The growing field of regenerative rehabilitation has great potential to improve clinical outcomes for individuals with disabilities. However, the science to elucidate the specific biological underpinnings of regenerative rehabilitation–based approaches is still in its infancy and critical questions regarding clinical translation and implementation still exist. In a recent roundtable discussion from International Consortium for Regenerative Rehabilitation stakeholders, key challenges to progress in the field were identified. The goal of this article is to summarize those discussions and to initiate a broader discussion among clinicians and scientists across the fields of regenerative medicine and rehabilitation science to ultimately progress regenerative rehabilitation from an emerging field to an established interdisciplinary one. Strategies and case studies from consortium institutions—including interdisciplinary research centers, formalized courses, degree programs, international symposia, and collaborative grants—are presented. We propose that these strategic directions have the potential to engage and train clinical practitioners and basic scientists, transform clinical practice, and, ultimately, optimize patient outcomes.
AB - The growing field of regenerative rehabilitation has great potential to improve clinical outcomes for individuals with disabilities. However, the science to elucidate the specific biological underpinnings of regenerative rehabilitation–based approaches is still in its infancy and critical questions regarding clinical translation and implementation still exist. In a recent roundtable discussion from International Consortium for Regenerative Rehabilitation stakeholders, key challenges to progress in the field were identified. The goal of this article is to summarize those discussions and to initiate a broader discussion among clinicians and scientists across the fields of regenerative medicine and rehabilitation science to ultimately progress regenerative rehabilitation from an emerging field to an established interdisciplinary one. Strategies and case studies from consortium institutions—including interdisciplinary research centers, formalized courses, degree programs, international symposia, and collaborative grants—are presented. We propose that these strategic directions have the potential to engage and train clinical practitioners and basic scientists, transform clinical practice, and, ultimately, optimize patient outcomes.
KW - Regenerative medicine
KW - Rehabilitation
KW - Tissue engineering
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UR - http://www.scopus.com/inward/citedby.url?scp=85082434844&partnerID=8YFLogxK
U2 - 10.1016/j.apmr.2020.01.007
DO - 10.1016/j.apmr.2020.01.007
M3 - Comment/debate
C2 - 32035141
AN - SCOPUS:85082434844
SN - 0003-9993
VL - 101
SP - 917
EP - 923
JO - Archives of Physical Medicine and Rehabilitation
JF - Archives of Physical Medicine and Rehabilitation
IS - 5
ER -