@article{0c50737af1de4afc98230f3ddf65b285,
title = "Targeted Expansion of Tissue-Resident CD8+ T Cells to Boost Cellular Immunity in the Skin",
abstract = "Tissue-resident memory (TRM) T cells provide a first line of host defense against pathogen invasion at environmental barrier tissues. Here, Hobbs and Nolz describe a mechanism to rapidly expand the number of antigen-specific TRM CD8+ T cells in the skin, using topical application of antigenic peptide to boost localized protective immunity.",
keywords = "CD8+ T cells, memory T cells, tissue-resident T cells, viral infection",
author = "Hobbs, {Samuel J.} and Nolz, {Jeffrey C.}",
note = "Funding Information: The authors thank Dr. Martin Richer for critical review of the manuscript, Dr. Ann Hill for helpful discussion, and Jake Harbour for technical assistance. We also acknowledge the OHSU Flow Cytometry core facility. This study was supported by National Institutes of Health ( NIH ) grants R01AI132404 , T32AI007472 , and F31AI140525 . Publisher Copyright: {\textcopyright} 2019 The Authors",
year = "2019",
month = dec,
day = "3",
doi = "10.1016/j.celrep.2019.10.126",
language = "English (US)",
volume = "29",
pages = "2990--2997.e2",
journal = "Cell Reports",
issn = "2211-1247",
publisher = "Cell Press",
number = "10",
}