TY - JOUR
T1 - Term elective induction of labour and perinatal outcomes in obese women
T2 - Retrospective cohort study
AU - Lee, V. R.
AU - Darney, B. G.
AU - Snowden, J. M.
AU - Main, E. K.
AU - Gilbert, W.
AU - Chung, J.
AU - Caughey, A. B.
N1 - Funding Information:
The authors would like to acknowledge William Lambert for editorial assistance. JMS is supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (grant number K99 HD079658-01).
Publisher Copyright:
© 2015 Royal College of Obstetricians and Gynaecologists.
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Objective To compare perinatal outcomes between elective induction of labour (eIOL) and expectant management in obese women. Design Retrospective cohort study. Setting Deliveries in California in 2007. Population Term, singleton, vertex, nonanomalous deliveries among obese women (n = 74 725). Methods Women who underwent eIOL at 37 weeks were compared with women who were expectantly managed at that gestational age. Similar comparisons were made at 38, 39, and 40 weeks. Results were stratified by parity. Chi-square tests and multivariable logistic regression were used for statistical comparison. Main outcome measures Method of delivery, severe perineal lacerations, postpartum haemorrhage, chorioamnionitis, macrosomia, shoulder dystocia, brachial plexus injury, respiratory distress syndrome. Results The odds of caesarean delivery were lower among nulliparous women with eIOL at 37 weeks [odds ratio (OR) 0.55, 95% confidence interval (CI) 0.34-0.90] and 39 weeks (OR 0.77, 95% CI 0.63-0.95) compared to expectant management. Among multiparous women with a prior vaginal delivery, eIOL at 37 (OR 0.39, 95% CI 0.24-0.64), 38 (OR 0.65, 95% CI 0.51-0.82), and 39 weeks (OR 0.67, 95% CI 0.56-0.81) was associated with lower odds of caesarean. Additionally, eIOL at 38, 39, and 40 weeks was associated with lower odds of macrosomia. There were no differences in the odds of operative vaginal delivery, lacerations, brachial plexus injury or respiratory distress syndrome. Conclusions In obese women, term eIOL may decrease the risk of caesarean delivery, particularly in multiparas, without increasing the risks of other adverse outcomes when compared with expectant management. Tweetable abstract Elective induction of labour in obese women does not increase risk of caesarean or other perinatal morbidities.
AB - Objective To compare perinatal outcomes between elective induction of labour (eIOL) and expectant management in obese women. Design Retrospective cohort study. Setting Deliveries in California in 2007. Population Term, singleton, vertex, nonanomalous deliveries among obese women (n = 74 725). Methods Women who underwent eIOL at 37 weeks were compared with women who were expectantly managed at that gestational age. Similar comparisons were made at 38, 39, and 40 weeks. Results were stratified by parity. Chi-square tests and multivariable logistic regression were used for statistical comparison. Main outcome measures Method of delivery, severe perineal lacerations, postpartum haemorrhage, chorioamnionitis, macrosomia, shoulder dystocia, brachial plexus injury, respiratory distress syndrome. Results The odds of caesarean delivery were lower among nulliparous women with eIOL at 37 weeks [odds ratio (OR) 0.55, 95% confidence interval (CI) 0.34-0.90] and 39 weeks (OR 0.77, 95% CI 0.63-0.95) compared to expectant management. Among multiparous women with a prior vaginal delivery, eIOL at 37 (OR 0.39, 95% CI 0.24-0.64), 38 (OR 0.65, 95% CI 0.51-0.82), and 39 weeks (OR 0.67, 95% CI 0.56-0.81) was associated with lower odds of caesarean. Additionally, eIOL at 38, 39, and 40 weeks was associated with lower odds of macrosomia. There were no differences in the odds of operative vaginal delivery, lacerations, brachial plexus injury or respiratory distress syndrome. Conclusions In obese women, term eIOL may decrease the risk of caesarean delivery, particularly in multiparas, without increasing the risks of other adverse outcomes when compared with expectant management. Tweetable abstract Elective induction of labour in obese women does not increase risk of caesarean or other perinatal morbidities.
KW - Caesarean delivery
KW - elective induction of labour
KW - maternal obesity
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U2 - 10.1111/1471-0528.13807
DO - 10.1111/1471-0528.13807
M3 - Article
C2 - 26840780
AN - SCOPUS:84952790960
SN - 1470-0328
VL - 123
SP - 271
EP - 278
JO - BJOG: An International Journal of Obstetrics and Gynaecology
JF - BJOG: An International Journal of Obstetrics and Gynaecology
IS - 2
ER -