The CD4+ T cell response to HIV-1

Louis J. Picker, Vernon C. Maino

Research output: Contribution to journalReview articlepeer-review

43 Scopus citations


Although virus-specific CD4+ T cells have proven to be a critical component of the immunologic control of chronic viral infections in a number of models, the role and even the existence of HIV-1-specific CD4+ T cells in human HIV-1 infection has been controversial. Recent advances in quantifying and functionally characterizing HIV-1-specific T cells may shed light on the participation of these cells in anti-HIV-1 host defense.

Original languageEnglish (US)
Pages (from-to)381-386
Number of pages6
JournalCurrent opinion in immunology
Issue number4
StatePublished - Aug 1 2000

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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