@article{59971986c429411db3fc483a89ae50a8,
title = "The chorionic gonadotropin α-subunit gene is on human chromosome 18 in JEG cells",
abstract = "The gene for the α subunit of human chorionic gonadotropin (hCG) has been tentatively assigned to human chromosome 18. This localization was accomplished through the use of Southern blot analysis. A full-length cDNA probe for the hCG α subunit and DNA isolated from a series of somatic hybrids between mouse and human cells were utilized to make this assignment. In addition, in situ hybridization with normal human peripheral blood lymphocytes as a source of human chromosomes and with the same cDNA probe confirmed this result. The presence of human chromosome 18 was required for the detection of DNA fragments characteristic of the α-hCG gene. These results are consistent with our previous observation that human chromosomes 10 and 18 are required for the production of hCG in cultured cells.",
author = "Hardin, \{J. W.\} and Riser, \{M. E.\} and Trent, \{J. M.\} and Kohler, \{P. O.\}",
year = "1983",
doi = "10.1073/pnas.80.20.6282",
language = "English (US)",
volume = "80",
pages = "6282--6285",
journal = "Proceedings of the National Academy of Sciences of the United States of America",
issn = "0027-8424",
publisher = "National Academy of Sciences",
number = "20 I",
}