TY - JOUR
T1 - The contemporary management of cancers of the sinonasal tract in adults
AU - Thawani, Rajat
AU - Kim, Myung Sun
AU - Arastu, Asad
AU - Feng, Zizhen
AU - West, Malinda T.
AU - Taflin, Nicholas F.
AU - Thein, Kyaw Zin
AU - Li, Ryan
AU - Geltzeiler, Mathew
AU - Lee, Nancy
AU - Fuller, Clifton David
AU - Grandis, Jennifer R.
AU - Floudas, Charalampos S.
AU - Heinrich, Michael C.
AU - Hanna, Ehab
AU - Chandra, Ravi A.
N1 - Publisher Copyright:
© 2022 The Authors. CA: A Cancer Journal for Clinicians published by Wiley Periodicals LLC on behalf of American Cancer Society.
PY - 2023/1/1
Y1 - 2023/1/1
N2 - Sinonasal malignancies make up <5% of all head and neck neoplasms, with an incidence of 0.5–1.0 per 100,000. The outcome of these rare malignancies has been poor, whereas significant progress has been made in the management of other cancers. The objective of the current review was to describe the incidence, causes, presentation, diagnosis, treatment, and recent developments of malignancies of the sinonasal tract. The diagnoses covered in this review included sinonasal undifferentiated carcinoma, sinonasal adenocarcinoma, sinonasal squamous cell carcinoma, and esthesioneuroblastoma, which are exclusive to the sinonasal tract. In addition, the authors covered malignances that are likely to be encountered in the sinonasal tract—primary mucosal melanoma, NUT (nuclear protein of the testis) carcinoma, and extranodal natural killer cell/T-cell lymphoma. For the purpose of keeping this review as concise and focused as possible, sarcomas and malignancies that can be classified as salivary gland neoplasms were excluded.
AB - Sinonasal malignancies make up <5% of all head and neck neoplasms, with an incidence of 0.5–1.0 per 100,000. The outcome of these rare malignancies has been poor, whereas significant progress has been made in the management of other cancers. The objective of the current review was to describe the incidence, causes, presentation, diagnosis, treatment, and recent developments of malignancies of the sinonasal tract. The diagnoses covered in this review included sinonasal undifferentiated carcinoma, sinonasal adenocarcinoma, sinonasal squamous cell carcinoma, and esthesioneuroblastoma, which are exclusive to the sinonasal tract. In addition, the authors covered malignances that are likely to be encountered in the sinonasal tract—primary mucosal melanoma, NUT (nuclear protein of the testis) carcinoma, and extranodal natural killer cell/T-cell lymphoma. For the purpose of keeping this review as concise and focused as possible, sarcomas and malignancies that can be classified as salivary gland neoplasms were excluded.
KW - head and neck neoplasms
KW - paranasal sinus neoplasms
KW - rare diseases
KW - sinonasal carcinoma
UR - http://www.scopus.com/inward/record.url?scp=85135440937&partnerID=8YFLogxK
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U2 - 10.3322/caac.21752
DO - 10.3322/caac.21752
M3 - Review article
C2 - 35916666
AN - SCOPUS:85135440937
SN - 0007-9235
VL - 73
SP - 72
EP - 112
JO - CA Cancer Journal for Clinicians
JF - CA Cancer Journal for Clinicians
IS - 1
ER -