The diagnosis and management of suspected lymphoma in general practice

Ashley R. Paquin, Emmanuella Oyogoa, Hannah Stowe McMurry, Thomas Kartika, Malinda West, Joseph J. Shatzel

Research output: Contribution to journalReview articlepeer-review


With rapid advancements in diagnosis and treatment of malignancies, the gap between generalists and subspecialists continues to widen, particularly in cancers like lymphoma where the spectrum of disease varies from indolent to rapidly progressive. Prior to establishing with a hematologist/oncologist, patients must be accurately and comprehensively diagnosed and managed for lymphoma in the generalist setting. In the following manuscript, we review the common clinical presentations in which should raise concern for lymphoma. We summarize the literature regarding the role of laboratory studies including complete blood count and peripheral blood flow cytometry, the recommendations for lymph node sampling, the role and selection of imaging modalities, and ideal patient monitoring for high-risk clinical syndromes that may be encountered in lymphoma.

Original languageEnglish (US)
Pages (from-to)3-13
Number of pages11
JournalEuropean Journal of Haematology
Issue number1
StatePublished - Jan 2023


  • lymphoma
  • primary care
  • workup

ASJC Scopus subject areas

  • Hematology


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