TY - JOUR
T1 - The Future of heart procurement with donation after circulatory death
T2 - Current practice and opportunities for advancement
AU - Ayer, Austin
AU - Schroder, Jacob N.
AU - Casalinova, Sarah
AU - Doberne, Julie W.
AU - Bryner, Benjamin S.
AU - Patel, Chetan B.
AU - DeVore, Adam D.
N1 - Publisher Copyright:
© 2022 International Society for Heart and Lung Transplantation
PY - 2022/10
Y1 - 2022/10
N2 - Heart Donation after Circulatory Death (DCD) has the potential to significantly increase the number of patients benefitting from heart transplantation. However, the expansion of DCD heart transplantation is currently limited by unanswered questions pertaining to best practices in DCD heart procurement. Additionally, significant variability exists within regulatory frameworks, professional guidelines, and published practices of DCD procurement processes. Here we describe the current practice and outstanding questions related to fundamental aspects of DCD heart procurement, including donor selection, premortem donor intervention, ischemic definitions, confirmation of circulatory death, and techniques for heart procurement and preservation. Addressing these key issues through research and consensus recommendations will facilitate the advancement of the field and ultimately expand the opportunity for heart transplantation to a greater number of patients.
AB - Heart Donation after Circulatory Death (DCD) has the potential to significantly increase the number of patients benefitting from heart transplantation. However, the expansion of DCD heart transplantation is currently limited by unanswered questions pertaining to best practices in DCD heart procurement. Additionally, significant variability exists within regulatory frameworks, professional guidelines, and published practices of DCD procurement processes. Here we describe the current practice and outstanding questions related to fundamental aspects of DCD heart procurement, including donor selection, premortem donor intervention, ischemic definitions, confirmation of circulatory death, and techniques for heart procurement and preservation. Addressing these key issues through research and consensus recommendations will facilitate the advancement of the field and ultimately expand the opportunity for heart transplantation to a greater number of patients.
KW - donation after circulatory death
KW - donor selection
KW - heart procurement
KW - heart transplantation
KW - normothermic perfusion
UR - http://www.scopus.com/inward/record.url?scp=85138836736&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85138836736&partnerID=8YFLogxK
U2 - 10.1016/j.healun.2022.06.016
DO - 10.1016/j.healun.2022.06.016
M3 - Review article
C2 - 35953351
AN - SCOPUS:85138836736
SN - 1053-2498
VL - 41
SP - 1385
EP - 1390
JO - Journal of Heart and Lung Transplantation
JF - Journal of Heart and Lung Transplantation
IS - 10
ER -