The Future of heart procurement with donation after circulatory death: Current practice and opportunities for advancement

Austin Ayer, Jacob N. Schroder, Sarah Casalinova, Julie W. Doberne, Benjamin S. Bryner, Chetan B. Patel, Adam D. DeVore

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations

Abstract

Heart Donation after Circulatory Death (DCD) has the potential to significantly increase the number of patients benefitting from heart transplantation. However, the expansion of DCD heart transplantation is currently limited by unanswered questions pertaining to best practices in DCD heart procurement. Additionally, significant variability exists within regulatory frameworks, professional guidelines, and published practices of DCD procurement processes. Here we describe the current practice and outstanding questions related to fundamental aspects of DCD heart procurement, including donor selection, premortem donor intervention, ischemic definitions, confirmation of circulatory death, and techniques for heart procurement and preservation. Addressing these key issues through research and consensus recommendations will facilitate the advancement of the field and ultimately expand the opportunity for heart transplantation to a greater number of patients.

Original languageEnglish (US)
Pages (from-to)1385-1390
Number of pages6
JournalJournal of Heart and Lung Transplantation
Volume41
Issue number10
DOIs
StatePublished - Oct 2022
Externally publishedYes

Keywords

  • donation after circulatory death
  • donor selection
  • heart procurement
  • heart transplantation
  • normothermic perfusion

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Transplantation

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