The genetics of hearing and balance in zebrafish

Teresa Nicolson

Research output: Contribution to journalReview articlepeer-review

198 Scopus citations


The zebrafish is an excellent model system for studying the molecular basis of inner ear development and function. The eggs develop ex utero and the ear is transparent for the first few weeks of life. Forward genetic screens and antisense technology have helped to elucidate the signaling pathways and molecules required for inner ear development and function. This review addresses the most recent advances in our understanding of how the ear forms and discusses the molecules in hair cells that are essential for sensing sound and movement in the zebrafish.

Original languageEnglish (US)
Pages (from-to)9-22
Number of pages14
JournalAnnual Review of Genetics
StatePublished - 2005
Externally publishedYes


  • Deafness
  • Development
  • Hair cells
  • Inner ear
  • Lateral line organ
  • Mechanotransduction

ASJC Scopus subject areas

  • Genetics


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