The High Energy Cost of Theta–Gamma Activity during REM Sleep

Anusha Mishra, Laura Lee Colgin

Research output: Contribution to journalShort surveypeer-review

1 Scopus citations


The occurrence of wake-like electroencephalography (EEG) traces during rapid-eye movement sleep (REM) has intrigued scientists for decades. A recent study by Bergel et al. (Nat. Commun. 2018;9;5364) imaged brain-wide hemodynamics in rats during wakefulness and sleep. The findings suggest that brain energy expenditure is highest during REM because of heightened theta and gamma activity.

Original languageEnglish (US)
Pages (from-to)239-241
Number of pages3
JournalTrends in Neurosciences
Issue number4
StatePublished - Apr 2019


  • gamma
  • hippocampus
  • neurovascular coupling
  • oscillations
  • theta

ASJC Scopus subject areas

  • Neuroscience(all)


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