The leech product saratin is a potent inhibitor of platelet integrin α₂β₁ and von Willebrand factor binding to collagen

Medicine & Life Sciences

• saratin 100%
• Leeches 62%
• Platelet Aggregation Inhibitors 50%
• von Willebrand Factor 49%
• Integrins 42%
• Collagen 33%
• Blood Platelets 16%
• Fibrillar Collagens 8%
• platelet membrane glycoprotein VI 5%
• Platelet Glycoprotein GPIb-IX Complex 4%
• Thromboxane A2 3%
• src-Family Kinases 3%
• Platelet-Rich Plasma 3%
• Vascular System Injuries 3%
• Platelet Activation 3%
• Hemostasis 2%
• Adenosine Diphosphate 2%
• Epitopes 2%
• Thrombosis 2%

Chemical Compounds

• Collagen 42%
• Glycoprotein 6%
• Thromboxane A2 4%
• Phosphotransferase Inhibitor 4%
• Plasma 4%
• ADP 3%
• Epitope 3%
• Shear 3%
• Flow 2%