The Life of a Fracture: Biologic Progression, Healing Gone Awry, and Evaluation of Union

Justin E. Hellwinkel; Theodore Miclau; Matthew T. Provencher; Chelsea S. Bahney; Zachary M. Working

doi:10.2106/JBJS.RVW.19.00221

The Life of a Fracture: Biologic Progression, Healing Gone Awry, and Evaluation of Union

Justin E. Hellwinkel, Theodore Miclau, Matthew T. Provencher, Chelsea S. Bahney, Zachary M. Working

Orthopaedics and Rehabilitation

Research output: Contribution to journal › Review article › peer-review

11 Scopus citations

Abstract

» New knowledge about the molecular biology of fracture-healing provides opportunities for intervention and reduction of risk for specific phases that are affected by disease and medications.» Modifiable and nonmodifiable risk factors can prolong healing, and the informed clinician should optimize each patient to provide the best chance for union.» Techniques to monitor progression of fracture-healing have not changed substantially over time; new objective modalities are needed.

Original language	English (US)
Pages (from-to)	E1900221
Journal	JBJS Reviews
Volume	8
Issue number	8
DOIs	https://doi.org/10.2106/JBJS.RVW.19.00221
State	Published - Aug 13 2020

ASJC Scopus subject areas

Surgery
Orthopedics and Sports Medicine

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10.2106/JBJS.RVW.19.00221

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title = "The Life of a Fracture: Biologic Progression, Healing Gone Awry, and Evaluation of Union",

abstract = "» New knowledge about the molecular biology of fracture-healing provides opportunities for intervention and reduction of risk for specific phases that are affected by disease and medications.» Modifiable and nonmodifiable risk factors can prolong healing, and the informed clinician should optimize each patient to provide the best chance for union.» Techniques to monitor progression of fracture-healing have not changed substantially over time; new objective modalities are needed.",

author = "Hellwinkel, {Justin E.} and Theodore Miclau and Provencher, {Matthew T.} and Bahney, {Chelsea S.} and Working, {Zachary M.}",

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N2 - » New knowledge about the molecular biology of fracture-healing provides opportunities for intervention and reduction of risk for specific phases that are affected by disease and medications.» Modifiable and nonmodifiable risk factors can prolong healing, and the informed clinician should optimize each patient to provide the best chance for union.» Techniques to monitor progression of fracture-healing have not changed substantially over time; new objective modalities are needed.

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The Life of a Fracture: Biologic Progression, Healing Gone Awry, and Evaluation of Union

Abstract

ASJC Scopus subject areas

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