The nice niece: Digoxin, St. John's wort, CYP3A4, P-glycoprotein

Michael P. Hutchens, Catherine Marcucci

Research output: Chapter in Book/Report/Conference proceedingChapter


This case discusses the pharmacokinetic interaction between digoxin and St. Johns's wort. Digoxin is a cytochrome P450 3A4 substrate and St. John's wort is a 3A4 inducer and also a P-glycoprotein inducer.

Original languageEnglish (US)
Title of host publicationA Case Approach to Perioperative Drug-Drug Interactions
PublisherSpringer New York
Number of pages3
ISBN (Electronic)9781461474951
ISBN (Print)9781461474944
StatePublished - Sep 15 2015

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'The nice niece: Digoxin, St. John's wort, CYP3A4, P-glycoprotein'. Together they form a unique fingerprint.

Cite this