The Non-ossifying Fibroma: A Case Report and Review of the Literature

Leah M. Bowers, Donald M. Cohen, Indraneel Bhattacharyya, James C. Pettigrew, Mary F. Stavropoulos

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


The non-ossifying fibroma (NOF) is a benign, non-neoplastic lesion most commonly seen in the metaphyses of the long bones in children. While rare, the NOF has been reported in the mandible. The NOF in the extra-gnathic skeleton has a characteristic radiographic appearance, is typically asymptomatic and has a variable histologic make-up. Correlation of the radiographic appearance, clinical presentation and histopathology allows for differentiation of the NOF from odontogenic and non-odontogenic cysts and tumors. We report a new case of this interesting entity and review the radiographic, clinical and histologic features of the gnathic NOF reported in the literature. A thorough search of the English language literature returned a total of 19 cases of NOF involving the gnathic bones.

Original languageEnglish (US)
Pages (from-to)203-210
Number of pages8
JournalHead and Neck Pathology
Issue number2
StatePublished - Jun 2013
Externally publishedYes


  • Benign fibrous histiocytoma
  • Fibrous cortical defect
  • Mandible
  • Non-ossifying fibroma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Otorhinolaryngology
  • Oncology


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