The Rebirth of a Phoenix: Ovarian Cancers Are Addicted to ErbB-3

Gordon B. Mills; Yosef Yarden

doi:10.1016/j.ccr.2010.02.023

The Rebirth of a Phoenix: Ovarian Cancers Are Addicted to ErbB-3

Gordon B. Mills, Yosef Yarden

Research output: Contribution to journal › Short survey › peer-review

19 Scopus citations

Abstract

Several cancer drugs intercept the ErbB family receptors EGFR (ErbB-1) and HER2 (ErbB-2). However, the therapeutic value of targeting ErbB-3 has been less clear. A report in this issue of Cancer Cell by Sheng et al. renews hopes that intercepting ErbB-3-mediated autocrine loops bears potential for treatment of ovarian cancer.

Original language	English (US)
Pages (from-to)	217-218
Number of pages	2
Journal	Cancer Cell
Volume	17
Issue number	3
DOIs	https://doi.org/10.1016/j.ccr.2010.02.023
State	Published - Mar 16 2010
Externally published	Yes

ASJC Scopus subject areas

Oncology
Cell Biology
Cancer Research

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10.1016/j.ccr.2010.02.023

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title = "The Rebirth of a Phoenix: Ovarian Cancers Are Addicted to ErbB-3",

abstract = "Several cancer drugs intercept the ErbB family receptors EGFR (ErbB-1) and HER2 (ErbB-2). However, the therapeutic value of targeting ErbB-3 has been less clear. A report in this issue of Cancer Cell by Sheng et al. renews hopes that intercepting ErbB-3-mediated autocrine loops bears potential for treatment of ovarian cancer.",

author = "Mills, {Gordon B.} and Yosef Yarden",

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AU - Yarden, Yosef

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N2 - Several cancer drugs intercept the ErbB family receptors EGFR (ErbB-1) and HER2 (ErbB-2). However, the therapeutic value of targeting ErbB-3 has been less clear. A report in this issue of Cancer Cell by Sheng et al. renews hopes that intercepting ErbB-3-mediated autocrine loops bears potential for treatment of ovarian cancer.

AB - Several cancer drugs intercept the ErbB family receptors EGFR (ErbB-1) and HER2 (ErbB-2). However, the therapeutic value of targeting ErbB-3 has been less clear. A report in this issue of Cancer Cell by Sheng et al. renews hopes that intercepting ErbB-3-mediated autocrine loops bears potential for treatment of ovarian cancer.

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The Rebirth of a Phoenix: Ovarian Cancers Are Addicted to ErbB-3

Abstract

ASJC Scopus subject areas

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