Abstract
A large number of prokaryotic as well as eukaryotic proteins are produced with amino terminal propeptides. These amino-terminal extensions are essential for mediating proper folding of their corresponding proteins and are also termed as intramolecular chaperones. Though these propeptides are highly specific and unique in their function, several common features have been identified and indicate that the overall mechanism by which they function may be very similar.
Original language | English (US) |
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Pages (from-to) | 629-636 |
Number of pages | 8 |
Journal | Journal of Biochemistry |
Volume | 115 |
Issue number | 4 |
DOIs | |
State | Published - Apr 1994 |
Externally published | Yes |
Keywords
- Intramolecular chaperone
- Propeptides
- Protein folding
- Subtilisin
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology