The toxicity of recombinant human interleukin-2 in rats following intravenous infusion

Y. L. Matory; A. E. Chang; E. H. Lipford; R. Braziel; C. L. Hyatt; S. A. Rosenberg

The toxicity of recombinant human interleukin-2 in rats following intravenous infusion

Y. L. Matory, A. E. Chang, E. H. Lipford, R. Braziel, C. L. Hyatt, S. A. Rosenberg

Research output: Contribution to journal › Article › peer-review

Abstract

Studies of recombinant interleukin-2 (RIL-2) administered by continuous intravenous infusion revealed hepatocellular toxicity and redistribution of lymphoid cells. This finding was different from the normal findings seen in rats receiving comparable infusions of the vehicle.

Original language	English (US)
Pages (from-to)	537-541
Number of pages	5
Journal	Journal of the National Medical Association
Volume	79
Issue number	5
State	Published - 1987
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

Cite this

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title = "The toxicity of recombinant human interleukin-2 in rats following intravenous infusion",

abstract = "Studies of recombinant interleukin-2 (RIL-2) administered by continuous intravenous infusion revealed hepatocellular toxicity and redistribution of lymphoid cells. This finding was different from the normal findings seen in rats receiving comparable infusions of the vehicle.",

author = "Matory, {Y. L.} and Chang, {A. E.} and Lipford, {E. H.} and R. Braziel and Hyatt, {C. L.} and Rosenberg, {S. A.}",

year = "1987",

language = "English (US)",

volume = "79",

pages = "537--541",

journal = "Journal of the National Medical Association",

issn = "1943-4693",

publisher = "National Medical Association",

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T1 - The toxicity of recombinant human interleukin-2 in rats following intravenous infusion

AU - Matory, Y. L.

AU - Chang, A. E.

AU - Lipford, E. H.

AU - Braziel, R.

AU - Hyatt, C. L.

AU - Rosenberg, S. A.

PY - 1987

Y1 - 1987

N2 - Studies of recombinant interleukin-2 (RIL-2) administered by continuous intravenous infusion revealed hepatocellular toxicity and redistribution of lymphoid cells. This finding was different from the normal findings seen in rats receiving comparable infusions of the vehicle.

AB - Studies of recombinant interleukin-2 (RIL-2) administered by continuous intravenous infusion revealed hepatocellular toxicity and redistribution of lymphoid cells. This finding was different from the normal findings seen in rats receiving comparable infusions of the vehicle.

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M3 - Article

C2 - 3495666

AN - SCOPUS:0023588221

SN - 1943-4693

VL - 79

SP - 537

EP - 541

JO - Journal of the National Medical Association

JF - Journal of the National Medical Association

IS - 5

ER -

The toxicity of recombinant human interleukin-2 in rats following intravenous infusion

Abstract

ASJC Scopus subject areas

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