The toxicity of recombinant human interleukin-2 in rats following intravenous infusion

Y. L. Matory, A. E. Chang, E. H. Lipford, R. Braziel, C. L. Hyatt, S. A. Rosenberg

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Studies of recombinant interleukin-2 (RIL-2) administered by continuous intravenous infusion revealed hepatocellular toxicity and redistribution of lymphoid cells. This finding was different from the normal findings seen in rats receiving comparable infusions of the vehicle.

Original languageEnglish (US)
Pages (from-to)537-541
Number of pages5
JournalJournal of the National Medical Association
Volume79
Issue number5
StatePublished - 1987
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine

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