Thick Heart, Wide QRS, Broad Differential

Stacey J. Howell, Babak Nazer

Research output: Contribution to journalArticlepeer-review


Routine electrocardiogram in a middle-aged man with left ventricular hypertrophy showed sinus rhythm, a short PR interval, and delta wave, confirming ventricular pre-excitation. Pre-excitation was fixed after a premature atrial complex and in atrial fibrillation, features diagnostic of a fasciculo-ventricular pathway. Genetic testing confirmed a diagnosis of hypertrophic cardiomyopathy. (Level of Difficulty: Intermediate.)

Original languageEnglish (US)
Pages (from-to)1363-1366
Number of pages4
JournalJACC: Case Reports
Issue number11
StatePublished - Sep 1 2021


  • atrial fibrillation
  • cardiomyopathy
  • electrophysiology
  • genetic disorders
  • inherited metabolic disorders

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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