Thrombotic microangiopathies

Thomas Deloughery

doi:10.1007/978-1-4419-7506-5_22

Thrombotic microangiopathies

Thomas Deloughery

Knight Cancer Institute

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The thrombotic microangiopathies (TMs) are a group of diseases that share the qualities of thrombocytopenia and microangiopathic hemolytic anemia resulting in microvascular occlusion and end-organ damage. The classic TMs are thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS). Since the early days of transplantation, it has been noted many patients developed a TM-type disease that was often fulminant and fatal. Research has been difficult due to lack of standardization of diagnostic criteria, and much controversy remains about the best therapy.

Original language	English (US)
Title of host publication	Blood and Marrow Transplant Handbook
Subtitle of host publication	Comprehensive Guide for Patient Care
Publisher	Springer New York
Pages	261-264
Number of pages	4
ISBN (Print)	9781441975058
DOIs	https://doi.org/10.1007/978-1-4419-7506-5_22
State	Published - 2011

ASJC Scopus subject areas

General Medicine

Access to Document

10.1007/978-1-4419-7506-5_22

Cite this

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abstract = "The thrombotic microangiopathies (TMs) are a group of diseases that share the qualities of thrombocytopenia and microangiopathic hemolytic anemia resulting in microvascular occlusion and end-organ damage. The classic TMs are thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS). Since the early days of transplantation, it has been noted many patients developed a TM-type disease that was often fulminant and fatal. Research has been difficult due to lack of standardization of diagnostic criteria, and much controversy remains about the best therapy.",

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AB - The thrombotic microangiopathies (TMs) are a group of diseases that share the qualities of thrombocytopenia and microangiopathic hemolytic anemia resulting in microvascular occlusion and end-organ damage. The classic TMs are thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS). Since the early days of transplantation, it has been noted many patients developed a TM-type disease that was often fulminant and fatal. Research has been difficult due to lack of standardization of diagnostic criteria, and much controversy remains about the best therapy.

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PB - Springer New York

ER -

Thrombotic microangiopathies

Abstract

ASJC Scopus subject areas

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