Thrombotic microangiopathies

Research output: Chapter in Book/Report/Conference proceedingChapter


The thrombotic microangiopathies (TMs) are a group of diseases that share the qualities of thrombocytopenia and microangiopathic hemolytic anemia resulting in microvascular occlusion and end-organ damage. The classic TMs are thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS). Since the early days of transplantation, it has been noted many patients developed a TM-type disease that was often fulminant and fatal. Research has been difficult due to lack of standardization of diagnostic criteria, and much controversy remains about the best therapy.

Original languageEnglish (US)
Title of host publicationBlood and Marrow Transplant Handbook
Subtitle of host publicationComprehensive Guide for Patient Care
PublisherSpringer New York
Number of pages4
ISBN (Print)9781441975058
StatePublished - 2011

ASJC Scopus subject areas

  • Medicine(all)


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