Time resolved diffuse reflectance and transmittance studies in tissue simulating phantoms. A comparison between theory and experiment

Steen J. Madsen; Michael S. Patterson; Brian C. Wilson; Young D. Park; J. David Moulton; Steven L. Jacques; Yaron Hefetz

Time resolved diffuse reflectance and transmittance studies in tissue simulating phantoms. A comparison between theory and experiment

Steen J. Madsen, Michael S. Patterson, Brian C. Wilson, Young D. Park, J. David Moulton, Steven L. Jacques, Yaron Hefetz

Research output: Contribution to journal › Conference article › peer-review

17 Scopus citations

Abstract

When a picosecond light pulse is incident on an optically turbid medium such as tissue, the temporal distribution of diffusely reflected and transmitted photons depends on the optical absorption and scattering properties of the medium. From diffusion theory it is possible to derive analytical expressions for the pulse shape in terms of the optical interaction coefficients of a homogeneous semi-infinite medium. Experimental tests of this model in tissue-simulating liquid phantoms of different geometries are presented here.

Original language	English (US)
Pages (from-to)	42-51
Number of pages	10
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	1431
State	Published - 1991
Externally published	Yes
Event	Proceedings of Time-Resolved Spectroscopy and Imaging of Tissues - Los Angeles, CA, USA Duration: Jan 23 1991 → Jan 24 1991

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

Cite this

Time resolved diffuse reflectance and transmittance studies in tissue simulating phantoms. A comparison between theory and experiment. / Madsen, Steen J.; Patterson, Michael S.; Wilson, Brian C. et al.
In: Proceedings of SPIE - The International Society for Optical Engineering, Vol. 1431, 1991, p. 42-51.

Research output: Contribution to journal › Conference article › peer-review

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AU - Madsen, Steen J.

AU - Patterson, Michael S.

AU - Wilson, Brian C.

AU - Park, Young D.

AU - Moulton, J. David

AU - Jacques, Steven L.

AU - Hefetz, Yaron

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AB - When a picosecond light pulse is incident on an optically turbid medium such as tissue, the temporal distribution of diffusely reflected and transmitted photons depends on the optical absorption and scattering properties of the medium. From diffusion theory it is possible to derive analytical expressions for the pulse shape in terms of the optical interaction coefficients of a homogeneous semi-infinite medium. Experimental tests of this model in tissue-simulating liquid phantoms of different geometries are presented here.

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M3 - Conference article

AN - SCOPUS:0025849467

SN - 0277-786X

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JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Proceedings of Time-Resolved Spectroscopy and Imaging of Tissues

Y2 - 23 January 1991 through 24 January 1991

ER -

Time resolved diffuse reflectance and transmittance studies in tissue simulating phantoms. A comparison between theory and experiment

Abstract

ASJC Scopus subject areas

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