Tobacco use among adults initiating treatment for HIV infection in rural uganda

Gina R. Kruse, David R. Bangsberg, Judith A. Hahn, Jessica E. Haberer, Peter W. Hunt, Conrad Muzoora, John P. Bennett, Jeffrey N. Martin, Nancy A. Rigotti

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


We conducted a longitudinal study of tobacco use among adults initiating antiretroviral therapy (ART) in Mbarara, Uganda where 11 % of men and 3 % of women use tobacco according to the 2011 Demographic and Health Survey. In a prospective cohort, self-reported tobacco use was assessed before starting ART and reassessed every 3-4 months. Plasma cotinine, a nicotine metabolite, was measured in a subset of adults pre-ART to verify self-report. Among 496 subjects, 50 (10 %) reported current tobacco use (20 % of men, 6 % of women). Most (53 %) adults with elevated cotinine levels (>15 ng/mL) reported no tobacco use. By 6 months after ART initiation, 33 % of tobacco users had quit (95 % CI 20-46 %). By 5 years, 64 % quit (95 % CI 47-77 %). Self-reported tobacco use among rural Ugandans starting ART was twice as common as among the local background population and use may be underreported. ART initiation could be an opportunity for tobacco cessation interventions.

Original languageEnglish (US)
Pages (from-to)1381-1389
Number of pages9
JournalAIDS and Behavior
Issue number7
StatePublished - Jul 2014
Externally publishedYes


  • Antiretroviral treatment initiation
  • Resource-limited setting
  • Smoking cessation
  • Socioeconomic status
  • Tobacco use

ASJC Scopus subject areas

  • Social Psychology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases


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