TOPSAN: A dynamic web database for structural genomics

Kyle Ellrott, Christian M. Zmasek, Dana Weekes, S. Sri Krishna, Constantina Bakolitsa, Adam Godzik, John Wooley

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


The Open Protein Structure Annotation Network (TOPSAN) is a web-based collaboration platform for exploring and annotating structures determined by structural genomics efforts. Characterization of those structures presents a challenge since the majority of the proteins themselves have not yet been characterized. Responding to this challenge, the TOPSAN platform facilitates collaborative annotation and investigation via a user-friendly webbased interface pre-populated with automatically generated information. Semantic web technologies expand and enrich TOPSAN's content through links to larger sets of related databases, and thus, enable data integration from disparate sources and data mining via conventional query languages. TOPSAN can be found at

Original languageEnglish (US)
Pages (from-to)D494-D496
JournalNucleic acids research
Issue numberSUPPL. 1
StatePublished - Jan 2011
Externally publishedYes

ASJC Scopus subject areas

  • Genetics


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