Treatment of corticosteroid dependent optic neuropathy with intravenous immunoglobulin

Daryl Kurz, Robert A. Egan, James T. Rosenbaum

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


PURPOSE: To report a patient with corticosteroid dependent optic neuropathy treated with intravenous immunoglobulin (IVIg). DESIGN: Interventional case report. METHODS: Records review. RESULTS: A 25-year-old woman developed bilateral vision loss with pain on eye movement in association with disk edema, dilated retinal veins, and hemorrhage. The vision improved markedly with prednisone, but she required a minimum of 20 mg/d despite concomitant therapy with methotrexate, cyclosporine, and/or mycophenolate mofetil. IVIg, 0.5 g/kg/d for 3 days each month with subsequent reduction in frequency, allowed discontinuation of all immunosuppression. CONCLUSIONS: Corticosteroid dependent optic neuropathy was successfully treated with IVIg.

Original languageEnglish (US)
Pages (from-to)1132-1133
Number of pages2
JournalAmerican journal of ophthalmology
Issue number6
StatePublished - Dec 2005
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


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