TY - JOUR
T1 - Treatment of corticosteroid dependent optic neuropathy with intravenous immunoglobulin
AU - Kurz, Daryl
AU - Egan, Robert A.
AU - Rosenbaum, James T.
N1 - Funding Information:
Supported in part by Research to Prevent Blindness, New York City (J.T.R., senior scholar). This work was supported by funds from the Rosenfeld Family Trust.
PY - 2005/12
Y1 - 2005/12
N2 - PURPOSE: To report a patient with corticosteroid dependent optic neuropathy treated with intravenous immunoglobulin (IVIg). DESIGN: Interventional case report. METHODS: Records review. RESULTS: A 25-year-old woman developed bilateral vision loss with pain on eye movement in association with disk edema, dilated retinal veins, and hemorrhage. The vision improved markedly with prednisone, but she required a minimum of 20 mg/d despite concomitant therapy with methotrexate, cyclosporine, and/or mycophenolate mofetil. IVIg, 0.5 g/kg/d for 3 days each month with subsequent reduction in frequency, allowed discontinuation of all immunosuppression. CONCLUSIONS: Corticosteroid dependent optic neuropathy was successfully treated with IVIg.
AB - PURPOSE: To report a patient with corticosteroid dependent optic neuropathy treated with intravenous immunoglobulin (IVIg). DESIGN: Interventional case report. METHODS: Records review. RESULTS: A 25-year-old woman developed bilateral vision loss with pain on eye movement in association with disk edema, dilated retinal veins, and hemorrhage. The vision improved markedly with prednisone, but she required a minimum of 20 mg/d despite concomitant therapy with methotrexate, cyclosporine, and/or mycophenolate mofetil. IVIg, 0.5 g/kg/d for 3 days each month with subsequent reduction in frequency, allowed discontinuation of all immunosuppression. CONCLUSIONS: Corticosteroid dependent optic neuropathy was successfully treated with IVIg.
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U2 - 10.1016/j.ajo.2005.06.053
DO - 10.1016/j.ajo.2005.06.053
M3 - Article
C2 - 16376665
AN - SCOPUS:29244439574
SN - 0002-9394
VL - 140
SP - 1132
EP - 1133
JO - American journal of ophthalmology
JF - American journal of ophthalmology
IS - 6
ER -