@article{3044c64574324d7aaece6520431467b5,
title = "Twelve-Month Retention in Opioid Agonist Treatment for Opioid Use Disorder Among Patients With and Without HIV",
abstract = "Although opioid agonist therapy (OAT) is associated with positive health outcomes, including improved HIV management, long-term retention in OAT remains low among patients with opioid use disorder (OUD). Using data from the Veterans Aging Cohort Study (VACS), we identify variables independently associated with OAT retention overall and by HIV status. Among 7,334 patients with OUD, 13.7% initiated OAT, and 27.8% were retained 12-months later. Likelihood of initiation and retention did not vary by HIV status. Variables associated with improved likelihood of retention included receiving buprenorphine (relative to methadone), receiving both buprenorphine and methadone at some point over the 12-month period, or diagnosis of HCV. History of homelessness was associated with a lower likelihood of retention. Predictors of retention were largely distinct between patients with HIV and patients without HIV. Findings highlight the need for clinical, systems, and research initiatives to better understand and improve OAT retention.",
keywords = "Buprenorphine, HIV, Methadone, Opioid-related disorders, Veteran health",
author = "Wyse, {Jessica J.} and McGinnis, {Kathleen A.} and Edelman, {E. Jennifer} and Gordon, {Adam J.} and Ajay Manhapra and Fiellin, {David A.} and Moore, {Brent A.} and Korthuis, {P. Todd} and Kennedy, {Amy J.} and Oldfield, {Benjamin J.} and Gaither, {Julie R.} and Gordon, {Kirsha S.} and Melissa Skanderson and Barry, {Declan T.} and Kendall Bryant and Stephen Crystal and Justice, {Amy C.} and Kraemer, {Kevin L.}",
note = "Funding Information: This work was supported by the National Institute on Alcohol Abuse and Alcoholism (R01 AA022886 (Kraemer) and U10 AA013566 (Justice)). Dr. Wyse{\textquoteright}s time was supported by Career Development Award 1IK2HX003007 from the U.S. Department of Veterans Affairs Health Services Research and Development, K12HS026370 from the Agency for Healthcare Research and Quality and resources from the VA Health Services Research and Development-funded Center to Improve Veteran Involvement in Care at the VA Portland Health Care System (CIN 13-404). Dr. Korthuis{\textquoteright} time was supported by the National Institutes of Health, National Institute on Drug Abuse (UG3DA044831, UG1DA015815). Dr. Edelman{\textquoteright}s time was supported by NIDA (R01DA040471). Dr. Crystal{\textquoteright}s time was supported by NIDA (R01DA047347) and NCATS (UL1TR003017 ) . A prior version of this research was presented at the College on Problems of Drug Dependence Annual Meeting, 2020. The authors have no relevant financial or non-financial interests to disclose. Funding Information: This work was supported by the National Institute on Alcohol Abuse and Alcoholism (R01 AA022886 (Kraemer) and U10 AA013566 (Justice)). Dr. Wyse{\textquoteright}s time was supported by Career Development Award 1IK2HX003007 from the U.S. Department of Veterans Affairs Health Services Research and Development, K12HS026370 from the Agency for Healthcare Research and Quality and resources from the VA Health Services Research and Development-funded Center to Improve Veteran Involvement in Care at the VA Portland Health Care System (CIN 13–404). Dr. Korthuis{\textquoteright} time was supported by the National Institutes of Health, National Institute on Drug Abuse (UG3DA044831, UG1DA015815). Dr. Edelman{\textquoteright}s time was supported by NIDA (R01DA040471). Dr. Crystal{\textquoteright}s time was supported by NIDA (R01DA047347) and NCATS (UL1TR003017). Publisher Copyright: {\textcopyright} 2021, This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply.",
year = "2022",
month = mar,
doi = "10.1007/s10461-021-03452-0",
language = "English (US)",
volume = "26",
pages = "975--985",
journal = "AIDS and Behavior",
issn = "1090-7165",
publisher = "Springer New York",
number = "3",
}