Ultrasound-modulated optical tomography for dense turbid media

Lihong Wang, Xuemei Zhao, Steven L. Jacques

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations


Continuous-wave ultrasonic modulation of scattered laser light has been used to image objects in tissue-simulating turbid media for the first time. We hypothesized that the ultrasound wave focused into the turbid media modulates the laser light passing through the ultrasonic focal zone. The modulated laser light collected by a photomultiplier tube reflects the local mechanical and optical properties in the focal zone. Buried objects in 5-cm thick tissue phantoms (absorption coefficient μa equals 0.1 cm-1, reduced scattering coefficient μs' equals 10 cm-1) were located with millimeter resolution by scanning and detecting alterations of the ultrasound-modulated optical signal.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherSociety of Photo-Optical Instrumentation Engineers
Number of pages12
ISBN (Print)0819420506, 9780819420503
StatePublished - 1996
Externally publishedYes
EventBiomedical Sensing, Imaging, and Tracking Technologies I - San Jose, CA, USA
Duration: Jan 29 1996Jan 31 1996


OtherBiomedical Sensing, Imaging, and Tracking Technologies I
CitySan Jose, CA, USA

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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