Ultrasound-modulated optical tomography for dense turbid media

Lihong Wang; Xuemei Zhao; Steven L. Jacques

doi:10.1117/12.238787

Ultrasound-modulated optical tomography for dense turbid media

Lihong Wang, Xuemei Zhao, Steven L. Jacques

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

4 Scopus citations

Abstract

Continuous-wave ultrasonic modulation of scattered laser light has been used to image objects in tissue-simulating turbid media for the first time. We hypothesized that the ultrasound wave focused into the turbid media modulates the laser light passing through the ultrasonic focal zone. The modulated laser light collected by a photomultiplier tube reflects the local mechanical and optical properties in the focal zone. Buried objects in 5-cm thick tissue phantoms (absorption coefficient μ_a equals 0.1 cm^-1, reduced scattering coefficient μ_s' equals 10 cm^-1) were located with millimeter resolution by scanning and detecting alterations of the ultrasound-modulated optical signal.

Original language	English (US)
Title of host publication	Proceedings of SPIE - The International Society for Optical Engineering
Publisher	Society of Photo-Optical Instrumentation Engineers
Pages	91-102
Number of pages	12
Volume	2676
ISBN (Print)	0819420506, 9780819420503
DOIs	https://doi.org/10.1117/12.238787
State	Published - 1996
Externally published	Yes
Event	Biomedical Sensing, Imaging, and Tracking Technologies I - San Jose, CA, USA Duration: Jan 29 1996 → Jan 31 1996

Other

Other	Biomedical Sensing, Imaging, and Tracking Technologies I
City	San Jose, CA, USA
Period	1/29/96 → 1/31/96

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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10.1117/12.238787

Cite this

Wang, L, Zhao, X & Jacques, SL 1996, Ultrasound-modulated optical tomography for dense turbid media. in Proceedings of SPIE - The International Society for Optical Engineering. vol. 2676, Society of Photo-Optical Instrumentation Engineers, pp. 91-102, Biomedical Sensing, Imaging, and Tracking Technologies I, San Jose, CA, USA, 1/29/96. https://doi.org/10.1117/12.238787

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abstract = "Continuous-wave ultrasonic modulation of scattered laser light has been used to image objects in tissue-simulating turbid media for the first time. We hypothesized that the ultrasound wave focused into the turbid media modulates the laser light passing through the ultrasonic focal zone. The modulated laser light collected by a photomultiplier tube reflects the local mechanical and optical properties in the focal zone. Buried objects in 5-cm thick tissue phantoms (absorption coefficient μa equals 0.1 cm-1, reduced scattering coefficient μs' equals 10 cm-1) were located with millimeter resolution by scanning and detecting alterations of the ultrasound-modulated optical signal.",

author = "Lihong Wang and Xuemei Zhao and Jacques, {Steven L.}",

year = "1996",

doi = "10.1117/12.238787",

language = "English (US)",

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volume = "2676",

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booktitle = "Proceedings of SPIE - The International Society for Optical Engineering",

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AB - Continuous-wave ultrasonic modulation of scattered laser light has been used to image objects in tissue-simulating turbid media for the first time. We hypothesized that the ultrasound wave focused into the turbid media modulates the laser light passing through the ultrasonic focal zone. The modulated laser light collected by a photomultiplier tube reflects the local mechanical and optical properties in the focal zone. Buried objects in 5-cm thick tissue phantoms (absorption coefficient μa equals 0.1 cm-1, reduced scattering coefficient μs' equals 10 cm-1) were located with millimeter resolution by scanning and detecting alterations of the ultrasound-modulated optical signal.

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Ultrasound-modulated optical tomography for dense turbid media

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