TY - JOUR
T1 - Use of prescribed opioids before and after bariatric surgery
T2 - prospective evidence from a U.S. multicenter cohort study
AU - King, Wendy C.
AU - Chen, Jia Yuh
AU - Belle, Steven H.
AU - Courcoulas, Anita P.
AU - Dakin, Gregory F.
AU - Flum, David R.
AU - Hinojosa, Marcelo W.
AU - Kalarchian, Melissa A.
AU - Mitchell, James E.
AU - Pories, Walter J.
AU - Spaniolas, Konstantinos
AU - Wolfe, Bruce M.
AU - Yanovski, Susan Z.
AU - Engel, Scott G.
AU - Steffen, Kristine J.
N1 - Publisher Copyright:
© 2017 American Society for Bariatric Surgery
PY - 2017/8
Y1 - 2017/8
N2 - Background Limited evidence suggests bariatric surgery may not reduce opioid analgesic use, despite improvements in pain. Objective To determine if use of prescribed opioid analgesics changes in the short and long term after bariatric surgery and to identify factors associated with continued and postsurgery initiated use. Setting Ten U.S. hospitals. Methods The Longitudinal Assessment of Bariatric Surgery-2 is an observational cohort study. Assessments were conducted presurgery, 6 months postsurgery, and annually postsurgery for up to 7 years until January 2015. Opioid use was defined as self-reported daily, weekly, or “as needed” use of a prescribed medication classified as an opioid analgesic. Results Of 2258 participants with baseline data, 2218 completed follow-up assessment(s) (78.7% were female, median body mass index: 46; 70.6% underwent Roux-en-Y gastric bypass). Prevalence of opioid use decreased after surgery from 14.7% (95% CI: 13.3–16.2) at baseline to 12.9% (95% CI: 11.5–14.4) at month 6 but then increased to 20.3%, above baseline levels, as time progressed (95% CI: 18.2–22.5) at year 7. Among participants without baseline opioid use (n = 1892), opioid use prevalence increased from 5.8% (95% CI: 4.7–6.9) at month 6 to 14.2% (95% CI: 12.2–16.3) at year 7. Public versus private health insurance, more pain presurgery, undergoing subsequent surgeries, worsening or less improvement in pain, and starting or continuing nonopioid analgesics postsurgery were significantly associated with higher risk of postsurgery initiated opioid use. Conclusion After bariatric surgery, prevalence of prescribed opioid analgesic use initially decreased but then increased to surpass baseline prevalence, suggesting the need for alternative methods of pain management in this population.
AB - Background Limited evidence suggests bariatric surgery may not reduce opioid analgesic use, despite improvements in pain. Objective To determine if use of prescribed opioid analgesics changes in the short and long term after bariatric surgery and to identify factors associated with continued and postsurgery initiated use. Setting Ten U.S. hospitals. Methods The Longitudinal Assessment of Bariatric Surgery-2 is an observational cohort study. Assessments were conducted presurgery, 6 months postsurgery, and annually postsurgery for up to 7 years until January 2015. Opioid use was defined as self-reported daily, weekly, or “as needed” use of a prescribed medication classified as an opioid analgesic. Results Of 2258 participants with baseline data, 2218 completed follow-up assessment(s) (78.7% were female, median body mass index: 46; 70.6% underwent Roux-en-Y gastric bypass). Prevalence of opioid use decreased after surgery from 14.7% (95% CI: 13.3–16.2) at baseline to 12.9% (95% CI: 11.5–14.4) at month 6 but then increased to 20.3%, above baseline levels, as time progressed (95% CI: 18.2–22.5) at year 7. Among participants without baseline opioid use (n = 1892), opioid use prevalence increased from 5.8% (95% CI: 4.7–6.9) at month 6 to 14.2% (95% CI: 12.2–16.3) at year 7. Public versus private health insurance, more pain presurgery, undergoing subsequent surgeries, worsening or less improvement in pain, and starting or continuing nonopioid analgesics postsurgery were significantly associated with higher risk of postsurgery initiated opioid use. Conclusion After bariatric surgery, prevalence of prescribed opioid analgesic use initially decreased but then increased to surpass baseline prevalence, suggesting the need for alternative methods of pain management in this population.
KW - Analgesia
KW - Bariatric surgery
KW - Laparoscopic adjustable gastric band
KW - Medication
KW - Narcotic
KW - Opioid
KW - Pain
KW - Roux-en-Y gastric bypass
KW - Severe obesity
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U2 - 10.1016/j.soard.2017.04.003
DO - 10.1016/j.soard.2017.04.003
M3 - Article
C2 - 28579202
AN - SCOPUS:85020021399
SN - 1550-7289
VL - 13
SP - 1337
EP - 1346
JO - Surgery for Obesity and Related Diseases
JF - Surgery for Obesity and Related Diseases
IS - 8
ER -